An interventional study of Chat and Enhanced Usual Care in Adolescent Drinking and Cannabis Use, sponsored by RAND. Recruiting at 3 sites in United States. Open to participants aged 12 Years to 19 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-09.
Sponsored by RAND · Not applicable, Interventional, and Prevention
Brief motivational interviewing intervention to address alcohol use among diverse teens 12-17.
The six-item CRAFFT will be used to screen teens at our partner clinics for risky AC use. For those that screen in as at-risk and express interest in the study, the teen's case manager will complete an online consent/assent form with the parent and teen that contains contact information for the teen so that investigators can follow up with the teen for surveys and intervention delivery or for providing an informational brochure. When the online consent/assent form is completed, the teen will be sent a personalized link to complete their baseline survey. Upon survey completion, the teen will receive a link that has their electronic gift card payment, and the case manager will be notified that a particular ID has completed the survey. The case manager will be informed by study staff whether to schedule that ID for enhanced usual care (EUC) or the Chat intervention. Investigators expect each teen to be scheduled within 30 days of completing their baseline survey to receive EUC or Chat. The informational brochure for the EUC will be handed to the teen during the visit or securely emailed, and Chat could take place either via a virtual or in-person visit. Whether or not the teen completes EUC or Chat, every teen will be followed by the RAND Survey Research Group to complete their follow-up web-based surveys based on timing of completion of their baseline survey. Teens will receive gift card incentives for completing the 3-month, 6-month, and 12-month surveys. Investigators will begin recruitment in month 9 of the project. Briefly, investigators expect to recruit from study month 9 to month 42 for the baseline survey. Investigators expect the Chat intervention to occur from months 9 to 42 the 3-month follow-up from months 12 to 45, 6-month from months 15 to 48, and the 12-month from months 21 to 53. Out of an anticipated 5,644 clients that our partner clinics will screen, investigators expect approximately 847 (15%) to screen in as at-risk on the CRAFFT and anticipate that approximately 500 (\~60%) will consent into the study.
44 studies on the registry are indexed under Underage Drinking; 13 are open to participants now.
This study's planned enrollment of 500 is above the median of 360 across 43 interventional studies indexed under Underage Drinking.
Browse Underage Drinking studies →RAND is the lead sponsor of 114 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
When the online consent/assent form is completed, the teen will be sent a personalized link to complete their baseline survey. Upon survey completion, the teen will receive a link that has their electronic gift card payment, and the case manager will be notified that a particular ID has completed the survey. The case manager will be informed by study staff whether to schedule that ID for enhanced usual care (EUC) or the Chat intervention. If they are randomized as EUC, the informational brochure for the EUC will be handed to the teen during the visit or securely emailed to them. Whether the teen completes EUC or Chat, every teen will be followed by the RAND Survey Research Group to complete their paid follow-up web-based surveys based on timing of completion of their baseline survey.
Behavioral: Enhanced Usual Care
When the online consent/assent form is completed, the teen will be sent a personalized link to complete their baseline survey. Upon survey completion, the teen will receive a link that has their electronic gift card payment, and the case manager will be notified that a particular ID has completed the survey. The case manager will be informed by study staff whether to schedule that ID for enhanced usual care (EUC) or the Chat Intervention. If they are randomized as Chat Intervention, Chat will take place either via a virtual or in-person visit. Whether the teen completes EUC or Chat, every teen will be followed by the RAND Survey Research Group to complete their paid follow-up web-based surveys based on timing of completion of their baseline survey.
Behavioral: Chat
Chat is a brief motivational interviewing intervention for partner clinic participants with an alcohol or cannabis use condition.
An informational brochure will be give to partner clinic participants with an alcohol or cannabis use condition.
Alcohol - change in frequency of use
We will assess both the number of times participants have used alcohol in the past three months (from none to 31 or more times) and the number of days in the past month participants report use of alcohol.
Time frame: Baseline to 3 months
Alcohol - change in frequency of use
We will assess both the number of times participants have used alcohol in the past three months (from none to 31 or more times) and the number of days in the past month participants report use of alcohol.
Time frame: 3 months to 6 months
Alcohol - change in frequency of use
We will assess both the number of times participants have used alcohol in the past six months (from none to 31 or more times) and the number of days in the past month participants report use of alcohol.
Time frame: 6 months to 12 months
Cannabis - change in frequency of use
We will assess both the number of times participants have used cannabis in the past three months (from none to 31 or more times) and the number of days in the past month participants report use of cannabis.
Time frame: Baseline to 3 months
Cannabis - change in frequency of use
We will assess both the number of times participants have used cannabis in the past three months (from none to 31 or more times) and the number of days in the past month participants report use of cannabis.
Time frame: 3 months to 6 months
Cannabis - change in frequency of use
We will assess both the number of times participants have used cannabis in the past six months (from none to 31 or more times) and the number of days in the past month participants report use of cannabis.
Time frame: 6 months to 12 months
Alcohol - change in consequences of use
Alcohol consequences (e.g., blacking out, regretted sexual situation) will be assessed with the Brief Young Adult Alcohol Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: Baseline to 3 months
Alcohol - change in consequences of use
Alcohol consequences (e.g., blacking out, regretted sexual situation) will be assessed with the Brief Young Adult Alcohol Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: 3 months to 6 months
Alcohol - change in consequences of use
Alcohol consequences (e.g., blacking out, regretted sexual situation) will be assessed with the Brief Young Adult Alcohol Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: 6 months to 12 months
Cannabis - change in consequences of use
Cannabis consequences (e.g., poor memory, too much time using) will be assessed with the Brief Marijuana Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: Baseline to 3 months
Cannabis - change in consequences of use
Cannabis consequences (e.g., poor memory, too much time using) will be assessed with the Brief Marijuana Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: 3 months to 6 months
Cannabis - change in consequences of use
Cannabis consequences (e.g., poor memory, too much time using) will be assessed with the Brief Marijuana Consequences Questionnaire (0 to 20 or more times, with higher scores indicating a worse outcome).
Time frame: 6 months to 12 months
Alcohol - change in time spent around peers
Participants will be asked how often they are with people their age who are using alcohol (1=never to 4=often).
Time frame: Baseline to 3 months
Alcohol - change in time spent around peers
Participants will be asked how often they are with people their age who are using alcohol (1=never to 4=often).
Time frame: 3 months to 6 months
Alcohol - change in time spent around peers
Participants will be asked how often they are with people their age who are using alcohol (1=never to 4=often).
Time frame: 6 months to 12 months
Cannabis - change in time spent around peers
Participants will be asked how often they are with people their age who are using cannabis (1=never to 4=often).
Time frame: Baseline to 3 months
Cannabis - change in time spent around peers
Participants will be asked how often they are with people their age who are using cannabis (1=never to 4=often).
Time frame: 3 months to 6 months
Cannabis - change in time spent around peers
Participants will be asked how often they are with people their age who are using cannabis (1=never to 4=often).
Time frame: 6 months to 12 months
Alcohol - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their alcohol use using a scale of 1-10 where 1 = "I have quit using alcohol and will never go back" and 10 = "I enjoy using alcohol and have decided never to change it."
Time frame: Baseline to 3 months
Alcohol - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their alcohol use using a scale of 1-10 where 1 = "I have quit using alcohol and will never go back" and 10 = "I enjoy using alcohol and have decided never to change it."
Time frame: 3 months to 6 months
Alcohol - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their alcohol use using a scale of 1-10 where 1 = "I have quit using alcohol and will never go back" and 10 = "I enjoy using alcohol and have decided never to change it."
Time frame: 6 months to 12 months
Cannabis - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their cannabis use using a scale of 1-10 where 1 = "I have quit using cannabis and will never go back" and 10 = "I enjoy using cannabis and have decided never to change it."
Time frame: Baseline to 3 months
Cannabis - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their cannabis use using a scale of 1-10 where 1 = "I have quit using cannabis and will never go back" and 10 = "I enjoy using cannabis and have decided never to change it."
Time frame: 3 months to 6 months
Cannabis - change in motivation to change use
We will measure motivation to change use by asking participants where they may be in their thinking about reducing or quitting their cannabis use using a scale of 1-10 where 1 = "I have quit using cannabis and will never go back" and 10 = "I enjoy using cannabis and have decided never to change it."
Time frame: 6 months to 12 months
Change in use of behavioral health care services
We will measure use of behavioral health care services (separate items for mental health and substance use), including whether there are unmet needs for behavioral health services (i.e., perceived a need to get treatment but didn't get it) and perceived reasons for those unmet needs (e.g., stigma, transportation, cost).
Time frame: Baseline to 3 months
Change in use of behavioral health care services
We will measure use of behavioral health care services (separate items for mental health and substance use), including whether there are unmet needs for behavioral health services (i.e., perceived a need to get treatment but didn't get it) and perceived reasons for those unmet needs (e.g., stigma, transportation, cost).
Time frame: 3 months to 6 months
Change in use of behavioral health care services
We will measure use of behavioral health care services (separate items for mental health and substance use), including whether there are unmet needs for behavioral health services (i.e., perceived a need to get treatment but didn't get it) and perceived reasons for those unmet needs (e.g., stigma, transportation, cost).
Time frame: 6 months to 12 months
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Started Apr 2025 (actual). Primary completion is estimated for Jul 2028, 39 months after the start.
Of 34 non-industry interventional studies with no phase under Underage Drinking, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 38. This study's planned 39 months is above that.
Counting every sponsor, half of 36 studies reached it within 24 months; a quarter within 12 and three quarters within 38.
How these figures are worked out, and which studies are left out of them.
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