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CompletedNCT04096274WISDOMUpdated Feb 20, 2024Results posted

Working to Implement and Sustain Digital Outcome Measures

An interventional study of Leadership for Organization Change and Implementation (LOCI) and Training and Technical Assistance Only in Implementation and Behavioral Symptoms, sponsored by Boise State University. Completed at 4 sites in United States. Open to participants aged 4 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-20.

Sponsored by Boise State University · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
686
Allocation
Randomized
Ages
4 Years and older
Sex
All
01

Study summary

This study will investigate the effects of an organizational implementation strategy called Leadership and Organizational Change for Implementation (LOCI), relative to training and technical assistance only, on fidelity to, and youth service outcomes of, a well-established digital measurement-based care intervention called the Outcomes Questionnaire-Analyst in outpatient community mental health clinics.

Read the detailed description

Using a cluster randomized, controlled, hybrid type III effectiveness-implementation design, this trial will investigate the effects of LOCI on the fidelity and and clinical outcomes of a digital measurement-based care (MBC) system called the Outcomes Questionnaire Analyst (OQ-A). The trial will enroll up to 22 outpatient mental health clinics that serve youth and randomly assign them using covariate constrained randomization to either LOCI or training and technical assistance only. Within each clinic, up to 2 first level leaders will be recruited (max N of 40 total) and a minimum of 3 clinicians will be recruited per site (60 total). Data on youth outpatients who receive services will be collected in two phases. In each phase, a unique cohort of 360 caregivers of youth who participate in services will be sampled from the participating clinics. Caregivers will report on the service outcomes and experiences of eligible youth who receive services. The total caregiver enrollment for two phases will be 720 (360*2).

02

Conditions studied

  • Implementation
  • Behavioral Symptoms

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Keywords

  • LOCI
  • measurement-based care
  • evidence-based practice
  • behavioral health
  • youth mental health
  • leadership
  • implementation science
03

Who can participate

Ages eligible
4 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Participants for this project will fall into four groups: 1) clinic executives and upper leaders (i.e., Chief Executive Officer, Executive Directors, program administrators, n=20), 2) clinic first-level leaders (i.e. clinical supervisors, n=20), 3) clinicians serving children with emotional and behavioral disorders (n=120), and 4) caregivers of children with emotional and behavioral disorders who receive outpatient mental health services within participating clinics (n=720). Caregivers will be recruited in two distinct cohorts of 360 each.

Inclusion criteria for all groups of participants are intentionally broad in line with the pragmatic nature of the trial.

Inclusion Criteria for Clinics

  1. Provide outpatient psychotherapy services to children ages 4 to 18 who have emotional and/ or behavioral disorders and their families
  2. Have at least 3 full time equivalent clinicians on staff
  3. Not currently implementing a digital measurement-based care system clinic wide

Inclusion Criteria for Executives and Upper Leaders

  1. Identified as Chief Executive Officer, Executive Director, or high-level administrator at an enrolled clinic

Inclusion Criteria for first-level leaders

  1. Identified as a clinical supervisor or clinical work-group supervisor/ leader at an enrolled clinic

Inclusion Criteria for Clinicians

  1. Employed as staff at participating clinic
  2. Provides outpatient mental health services (psychotherapy) to youth clients

Inclusion Criteria for Caregivers of Youth Who Receive Services at Participating Clinics

  1. Child is ages 4 to 18 years at intake,
  2. Child has been diagnosed with an emotional or behavioral disorder by clinic staff
  3. Clinical staff at the site determined that the youth's treatment needs can be appropriately addressed by the clinic
04

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
686 participants (actual)

Study arms

  • Experimental
    LOCI (Intervention)

    In clinics assigned to the LOCI condition, executives and first-level leaders will receive leadership training and coaching to support implementation of the OQ-A system. In addition, leaders and clinicians in this condition will receive training and technical assistance to implement the OQ-A measurement-based care system.

    Behavioral: Leadership for Organization Change and Implementation (LOCI) · Behavioral: Training and Technical Assistance Only

  • Active comparator
    Training and Technical Assistance only (Control)

    In clinics assigned to the control group, leaders and clinicians will receive training and technical assistance to implement the OQ-A measurement-based care system. In addition, to support enrollment in this condition, leaders in this condition will be offered access to general web-based leadership seminars.

    Behavioral: Training and Technical Assistance Only

Interventions

  • BehavioralLeadership for Organization Change and Implementation (LOCI)

    LOCI is a multicomponent implementation strategy that engages organizational executives and first-level leaders (i.e., those who administratively supervise clinicians) to build an organizational climate to support the implementation of a focal evidence-based practice (EBP) with fidelity. In this study, the focal EBP is the OQ-A system. LOCI includes two overarching components: (1) monthly organizational strategy meetings between executives and LOCI consultants/trainers to develop and embed policies, procedures, and practices that support implementation of a focal EBP, and (2) training and coaching for first-level leaders, to develop their skills in leading implementation. The aim of these components is to develop an organizational implementation climate in which clinicians' perceive that use of the OQ-A with high fidelity is expected, supported, and rewarded.

  • BehavioralTraining and Technical Assistance Only

    All leaders and clinicians in participating clinics will receive standardized OQ-A training and technical assistance provided by the OQ-A purveyor organization. This includes an initial, 6-hr, in-person OQ-A training; two, live, virtual, 1-hr booster trainings, offered 3 and 5 months after the initial training; and, year-round technical assistance from the OQ-A purveyor organization. Technical assistance includes virtual training sessions, online library of training videos, and customer care representative for technical support. In addition, to encourage participation in the study, a set of four 1-hr, web-based general leadership seminars will be offered to leaders in the control condition. These will cover topics ranging from effective leadership, to giving effective feedback.

05

What researchers measure

Primary outcomes

  1. Percentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)

    Fidelity to the OQ-A will be measured by using electronic meta-data from the OQ-A system combined with caregiver reported information on the number of sessions the youth attended. For each youth, a fidelity index will be generated that represents the product of two quantities: (a) the youth's completion rate (i.e., number of measures administered relative to the number of sessions attended within the 6-month observation period), and (b) the youth's viewing rate (i.e., the number of feedback reports viewed by the clinician relative to the number of measures administered). Note that this product is equivalent to the ratio of viewed feedback reports to total sessions; it represents an events/trials proportion. MBC fidelity index scores summarize the level of MBC fidelity experienced by each youth (range=0-1). Higher scores indicate the youth experienced greater fidelity to MBC.

    Time frame: 0-6 months after youth's baseline/ entry into treatment

  2. Change From Baseline to 6-months in Youth Total Problems Score on the Short Form Assessment for Children (SAC) - Phase I Cohort

    The SAC Total Problem Score is a 48-item measure of youth internalizing (e.g., anxious, depressed) and externalizing (e.g., aggressive, noncompliant, overactive) behaviors (range=0-96) completed by caregivers of youth. Total Problem Score was assessed at baseline (youth's entry into treatment) and monthly for 6 months, change from baseline to month 6 is reported.

    Time frame: 0-6 months after youth's baseline/ entry into treatment

  3. Change From Baseline to 6-months in Youth Total Problems Score on the Short-form Assessment for Children (SAC) - Phase II Cohort

    The SAC Total Problem Score is a 48-item measure of youth internalizing (e.g., anxious, depressed) and externalizing (e.g., aggressive, noncompliant, overactive) behaviors (range=0-96) completed by caregivers of youth. Total Problem Score was assessed at baseline (youth's entry into treatment) and monthly for 6 months, change from baseline to month 6 is reported.

    Time frame: 0-6 months after youth's baseline/ entry into treatment

06

Results

Posted Feb 20, 2024

Participant flow

Phase I
Participant flow — Phase I
MilestoneLOCI (Intervention)Training and Technical Assistance Only (Control)
Started117117
Completed112112
Not completed55
Withdrew: Lost to follow-up55
Phase II
Participant flow — Phase II
MilestoneLOCI (Intervention)Training and Technical Assistance Only (Control)
Started269183
Completed258172
Not completed1111
Withdrew: Lost to follow-up1111

Outcome measures

PrimaryPercentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)

Fidelity to the OQ-A will be measured by using electronic meta-data from the OQ-A system combined with caregiver reported information on the number of sessions the youth attended. For each youth, a fidelity index will be generated that represents the product of two quantities: (a) the youth's completion rate (i.e., number of measures administered relative to the number of sessions attended within the 6-month observation period), and (b) the youth's viewing rate (i.e., the number of feedback reports viewed by the clinician relative to the number of measures administered). Note that this product is equivalent to the ratio of viewed feedback reports to total sessions; it represents an events/trials proportion. MBC fidelity index scores summarize the level of MBC fidelity experienced by each youth (range=0-1). Higher scores indicate the youth experienced greater fidelity to MBC.

Time frame:
0-6 months after youth's baseline/ entry into treatment
Reported as:
Mean · percentage fidelity achieved
Percentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)
percentage fidelity achievedLOCI (Intervention)Training and Technical Assistance Only (Control)
Percentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)23.1 ± 9.03.4 ± 2.5
Statistical analysis
  • LOCI (Intervention) vs Training and Technical Assistance Only (Control) · Mixed Models Analysis · p = .014
PrimaryChange From Baseline to 6-months in Youth Total Problems Score on the Short Form Assessment for Children (SAC) - Phase I Cohort

The SAC Total Problem Score is a 48-item measure of youth internalizing (e.g., anxious, depressed) and externalizing (e.g., aggressive, noncompliant, overactive) behaviors (range=0-96) completed by caregivers of youth. Total Problem Score was assessed at baseline (youth's entry into treatment) and monthly for 6 months, change from baseline to month 6 is reported.

Time frame:
0-6 months after youth's baseline/ entry into treatment
Reported as:
Mean · units on a scale
Change From Baseline to 6-months in Youth Total Problems Score on the Short Form Assessment for Children (SAC) - Phase I Cohort
units on a scaleLOCI (Intervention)Training and Technical Assistance Only (Control)
Change From Baseline to 6-months in Youth Total Problems Score on the Short Form Assessment for Children (SAC) - Phase I Cohort-8.17 ± 1.19-4.04 ± 1.15
Statistical analysis
  • LOCI (Intervention) vs Training and Technical Assistance Only (Control) · Mixed Models Analysis · p = .023
PrimaryPercentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)

Fidelity to the OQ-A will be measured by using electronic meta-data from the OQ-A system combined with caregiver reported information on the number of sessions the youth attended. For each youth, a fidelity index will be generated that represents the product of two quantities: (a) the youth's completion rate (i.e., number of measures administered relative to the number of sessions attended within the 6-month observation period), and (b) the youth's viewing rate (i.e., the number of feedback reports viewed by the clinician relative to the number of measures administered). Note that this product is equivalent to the ratio of viewed feedback reports to total sessions; it represents an events/trials proportion. MBC fidelity index scores summarize the level of MBC fidelity experienced by each youth (range=0-1). Higher scores indicate the youth experienced greater fidelity to MBC.

Time frame:
0-6 months after youth's baseline/ entry into treatment
Reported as:
Mean · percentage fidelity achieved
Percentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)
percentage fidelity achievedLOCI (Intervention)Training and Technical Assistance Only (Control)
Percentage Fidelity to the OQ-A System Experienced by the Youth (0-100%)5.65 ± 4.790.97 ± 1.27
Statistical analysis
  • LOCI (Intervention) vs Training and Technical Assistance Only (Control) · Mixed Models Analysis · p = .188
PrimaryChange From Baseline to 6-months in Youth Total Problems Score on the Short-form Assessment for Children (SAC) - Phase II Cohort

The SAC Total Problem Score is a 48-item measure of youth internalizing (e.g., anxious, depressed) and externalizing (e.g., aggressive, noncompliant, overactive) behaviors (range=0-96) completed by caregivers of youth. Total Problem Score was assessed at baseline (youth's entry into treatment) and monthly for 6 months, change from baseline to month 6 is reported.

Time frame:
0-6 months after youth's baseline/ entry into treatment
Reported as:
Mean · units on a scale
Change From Baseline to 6-months in Youth Total Problems Score on the Short-form Assessment for Children (SAC) - Phase II Cohort
units on a scaleLOCI (Intervention)Training and Technical Assistance Only (Control)
Change From Baseline to 6-months in Youth Total Problems Score on the Short-form Assessment for Children (SAC) - Phase II Cohort-4.82 ± .70-5.19 ± 1.02
Statistical analysis
  • LOCI (Intervention) vs Training and Technical Assistance Only (Control) · Mixed Models Analysis · p = .782

Adverse events

Collected over Adverse event data were not collected for caregivers, who were the ones formally enrolled in the study.. Non-serious events are listed at a 5% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
LOCI (Intervention)———
Training and Technical Assistance Only (Control)———

Baseline characteristics

The data presented below reflects characteristics of youth as reported by their enrolled caregivers. With the exception of the family variables noted below, data on caregivers was not reported. Required fields for age, race, and sex refer to caregivers and therefore have values of 0 because this data was not reported. Please also note that the baseline characteristics shown below are reported separately for Phase I and Phase II of the trial because each phase was enrolled as a separate cohort.

Age, Categorical
Age, Categorical(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
<=18 years000
Between 18 and 65 years000
>=65 years000
Sex/Gender, Customized
Sex/Gender, Customized(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
Male000
Female000
Prefer not to disclose000
Race/Ethnicity, Customized
Race/Ethnicity, Customized(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
American Indian or Alaskan Native000
Asian000
Black or African American000
Pacific Islander or Hawaiian Native000
Prefer to self-describe000
Prefer not to disclose000
More than one race (Multiracial)000
White000
Unknown or not reported000
Phase I: Youth Short-form Assessment for Children (SAC) Total Problem Score
Phase I: Youth Short-form Assessment for Children (SAC) Total Problem Score(units on a scale)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
Mean37.1 ± 13.634.1 ± 12.835.6 ± 13.2
Phase I: Youth received prior mental health treatment
Phase I: Youth received prior mental health treatment(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
Count of participants6658124
Phase I: Family Income
Phase I: Family Income(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
Less than $25,750272047
$25,751 to $35,535191837
$35,536 to $51,500192039
More than $51,5005059109
Unknown or not reported202
Phase I: Parent Highest Education Level
Phase I: Parent Highest Education Level(Participants)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
High school graduate/GED or less252348
Associate's degree or some college484290
Bachelor's degree262854
Graduate degree182442
Unknown or not reported000
Phase I: Youth age
Phase I: Youth age(years)LOCI (Intervention)Training and Technical Assistance Only (Control)Total
Mean11.3 ± 3.712.1 ± 4.011.7 ± 3.8

11 further baseline measures are reported on the registry.

07

Study locations

4 sites
  • University of California, San Diego
    San Diego, California 92093, United States
  • University of Central Florida
    Orlando, Florida 32816, United States
  • Boise State University
    Boise, Idaho 83725, United States
  • University of Pennsylvania
    Philadelphia, Pennsylvania 19104, United States
08

References and documents

Study documents

  • Protocol and statistical analysis plan · Dec 21, 2023

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Registry details

Key details

Study ID
NCT04096274
Lead sponsor
Boise State University
Collaborators
University of California, San Diego, University of Central Florida, University of Pennsylvania, National Institute of Mental Health (NIMH)
Responsible party
Sponsor
First posted
Sep 19, 2019
Start date
Oct 1, 2019
Primary completion
Sep 17, 2022
Completion
Sep 17, 2022
Results posted
Feb 20, 2024
Last update
Feb 20, 2024

Study contacts

Nate Williams, PhD
principal investigator · Boise State University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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