An observational study in Eosinophilic Esophagitis (EoE), sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-10-09.
Sponsored by Mayo Clinic · Observational
Is there a difference in the eating process for patients with active Eosinophilic Esophagitis (EoE) and those with inactive disease?
Eosinophilic esophagitis (EoE) patients develop adapted eating behaviors to prevent symptoms. These patients tend to cut their food small, chew extensively, take copious liquids with meals, and avoid foods that cause symptoms. No studies to date have directly evaluated these eating behaviors in patients with EoE with observation. Furthermore, none of the investigators' current metrics for patient symptom assessment visually evaluate the eating process nor are they compared before and after treatment. As a result, it is unclear if a patient's subjective perception of their eating difficulties and improvement matches with objective measures.
322 studies on the registry are indexed under Esophagitis; 37 are open to participants now.
This study's enrollment of 31 is below the median of 100 across 91 observational studies indexed under Esophagitis.
Browse Esophagitis studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Individuals with EoE that are being seen at Mayo Clinic Esophageal Clinic will be approached. Controls will be individuals who do not have an EoE diagnosis.
Exclusion Criteria:
Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals who have EoE who have not been treated or have not achieved remission from treatment.
Behavioral: Observed eating session
Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals who have EoE who are have achieved remission from treatment.
Behavioral: Observed eating session
Observed eating session of Jimmy John's turkey or vegetarian sandwich with water among individuals without EoE.
Behavioral: Observed eating session
Eating a Jimmy Johns turkey or vegetarian sandwich
Observed eating session
number of bites of patient's with EoE and controls eating a Jimmy John's sandwich
Time frame: 15-90 minutes
Food slowness during eating session
number of bites that felt stuck among patients with EoE and controls when eating a Jimmy John's sandwich
Time frame: 15-90 minutes
Water during eating session
amount of water drank of patients with EoE and controls eating a Jimmy John's sandiwch
Time frame: 15-90 minutes
Eosinophilic Esophagitis activity Index (EEsAI) questionnaire
The EEsAI Pro uses the VDQ is visual dysphagia question AMS is avoidance, modification, slow eating question . These two along with questions on frequency of, duration of, pain associated with dysphagia make up the PRO (patient reported outcomes). The PRO is a number (0-100) calculated from the answer to the questions. A PRO \< 20 defines asymptomatic EoE.
Time frame: 10-15 minutes
Eosinophilic Esophagitis Quality of Life questionnaire
Higher score denote better quality of life. 0-4 as follows 4=not at all, 3=Slightly 2=moderately, 1=Quite a bit, 0= Extremely
Time frame: 10-15 minutes
This study is completed, as verified in Oct 2019. You cannot join it, but the record below documents what was studied.
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