An interventional study of Lidocaine in Thyroid Cancer, Neck Cancer and Recurrent Laryngeal Nerve Injuries, sponsored by Bo Wang,MD. Status unknown at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-09-18.
Sponsored by Bo Wang,MD · Not applicable, Interventional, and Treatment
In recent years, the application of intraoperative recurrent laryngeal nerve monitoring in thyroid surgery has greatly reduced the complications of recurrent laryngeal nerve injury. The use of intraoperative neurological monitoring requires the reduction of the dose of neuromuscular blockade, which often leads to muscle tremors during the application of electrical energy, which affects the fine separation around the muscles. This study explored the effect of local application of lidocaine on reducing muscle tremor during surgery and its optimal dose.
According to the random number method, eligible patients were randomly divided into 2 groups. Group A was the conventional surgery group, and Group B was the lidocaine group. The operative time for the separation of the sternocleidomastoid muscle from the two groups of patients was analyzed, as well as the length of time for the search for the accessory nerve and the effect of intraoperative nerve monitoring on the EMG signal.
785 studies on the registry are indexed under Thyroid Neoplasms; 204 are open to participants now.
This study's planned enrollment of 40 is below the median of 53 across 520 interventional studies indexed under Thyroid Neoplasms.
Browse Thyroid Neoplasms studies →Bo Wang,MD is the lead sponsor of 5 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Metastases
Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Induction of anesthesia according to conventional neuromuscular blockade dose, no neuromuscular blockade drug maintenance during lateral neck dissection.
Anesthesia induction was performed according to conventional nerve monitoring neuromuscular blockade doses and lateral neck dissection was performed. When local muscle tremors occur, lidocaine is injected locally to eliminate muscle tremors.
Drug: Lidocaine
Local injection of lidocaine reduces muscle tremor
dose of muscle relaxant drugs
dose of muscle relaxant drugs
Time frame: At the end of surgery
dose of lidocaine
dose of lidocaine
Time frame: At the end of surgery
Number of nerve signal loss cases
Number of nerve signal loss cases
Time frame: At the end of surgery
Anatomical time of accessory nerve
Anatomical time of accessory nerve
Time frame: At the end of surgery
The satisfaction of sternocleidomastoid muscle separation
The visual score was 5 points for the most satisfaction and 0 points for the most dissatisfied.
Time frame: At the end of surgery
This study is status unknown, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Lidocaine
Bo Wang,MD