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Status unknownNCT03511950Updated Sep 29, 2022

The Relationship Between the Change of Resting Energy Expenditure and Nutritional Status .

An observational study in Peritonitis, Resting Energy Expenditure and Nutrition, sponsored by Peking University First Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2022-09-29.

Sponsored by Peking University First Hospital · Observational

The sponsor has not verified this record recently (last verified Sep 2022), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
30
Ages
18 Years to 80 Years
Sex
All
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Study summary

Peritonitis is a common and devastating complication in patients on peritoneal dialysis (PD). It is a known fact that persistent inflammatory state and nutritional deterioration are closely associated with increased mortality in PD patients.And resting energy expenditure(REE) is significantly increased in acute and chronic inflammation in patients with chronic kidney disease (including dialysis patients).However,it is limited to the changing trend and duration of REE in peritonitis.Investigators hypothesize that the increase in total energy consumption resulting from the increase of REE which may accompany with decreased energy intake will lead to negative energy balance and nutritional deterioration, which may affect the prognosis of patients.Therefore,a prospective cohort study will be designed to dynamically research the change of REE accompanied with the nutrition status in peritonitis and provide the basis for peritonitis management in the future.

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Conditions studied

  • Peritonitis
  • Resting Energy Expenditure
  • Nutrition

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03

In context

Peritonitis

185 studies on the registry are indexed under Peritonitis; 25 are open to participants now.

This study's planned enrollment of 30 is below the median of 127 across 59 observational studies indexed under Peritonitis.

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Lead sponsor

Peking University First Hospital is the lead sponsor of 378 studies on the registry; 178 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

PD patients with confirm diagnosis of peritonitis

Inclusion criteria

  • Receiving PD for>3 months
  • Age between 18 and 80 years
  • Confirm diagnosis of peritonitis

Exclusion criteria

Exclusion Criteria:

  • Disability
  • Other acute complications: including systemic infections except for peritonitis, acute cardia-cerebrovascular disease in one month
  • Active hepatitis and musculoskeletal diseases in the past
  • Cancer and is treated with chemoradiotherapy within 1 year
  • Severe edema of the whole body or a large amount of body cavity effusion
  • Thyroid dysfunction
  • History of hormonal drugs use
  • During pregnancy or lactation
  • Mental disorder
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. The relationship between the change of REE and the change of albumin

    Method: REE, indirect calorimetry

    Time frame: 90 days

Secondary outcomes

  1. The relationship between the change of REE and the change of BMI

    The relationship between the change of REE and the change of BMI during 90 days after peritonitis

    Time frame: 90 days

  2. The relationship between the change of REE and the change of handgrip strength

    The relationship between the change of REE and the change of handgrip strength during 90 days after peritonitis

    Time frame: 90 days

  3. The relationship between the change of REE and the change of Fat mass

    Method: REE, indirect calorimetry; Fat mass, Bioelectrical impedance

    Time frame: 90 days

  4. The relationship between the change of REE and the change of lean body mass

    Method: REE, indirect calorimetry; lean body mass, Bioelectrical impedance

    Time frame: 90 days

Other outcomes

  1. The relationship between the change of REE and the outcome of patients

    outcome including death and transfer to hemodialysis

    Time frame: 90 days or 180days

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Study locations

1 of 1 sites recruiting
  • Peking University First Hospital
    Beijing, China
    Recruiting
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 29, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03511950
Lead sponsor
Peking University First Hospital
Responsible party
Dong Jie (Clinical Professor in Renal Division, Department of Medicine, Peking University First Hospital) — Principal investigator
First posted
Apr 30, 2018
Start date
Apr 1, 2021
Primary completion
Aug 30, 2023 (estimated)
Completion
Oct 30, 2023 (estimated)
Last update
Sep 29, 2022

Study contacts

Jie Dong
Contact
jie.dong@bjmu.edu.cn
13911841538

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.

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