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CompletedNCT03498495SMARTUpdated Jul 10, 2023

Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury

An interventional study of Self-Monitoring Activity-restriction and Relaxation Training (SMART) in Brain Injury Traumatic Mild, sponsored by Children's Hospital Medical Center, Cincinnati. Completed at 1 site in United States. Open to participants aged 11 Years to 18 Years. Per ClinicalTrials.gov, last updated 2023-07-10.

Sponsored by Children's Hospital Medical Center, Cincinnati · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
74
Allocation
Randomized
Ages
11 Years to 18 Years
Sex
All
01

Study summary

SMART is an interactive web-based program that will allow youth with mild traumatic brain injuries (mTBI) to monitor their symptoms and receive education on problem-solving and coping strategies. This study will evaluate the effectiveness of SMART as a means of improving symptom-management, coping skills, and general well-being during recovery from mTBI. Half of participants will receive the SMART intervention, while half will receive usual care.

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Conditions studied

03

Who can participate

Ages eligible
11 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • 11-18 years old
  • Sustained mTBI within the past week

Exclusion criteria

Exclusion Criteria:

  • Patient and/or family do not speak and read English
  • Patient and/or family do not have Internet access
  • Patient experiencing more severe brain injury (Glasgow coma score \<13)
  • Patient with more than one moderate extracranial injury
  • Patients with non-mTBI reasons for altered mental status
  • Patients with severe pre-existing neurologic or cognitive disorders or other disorders that may impair ability to participate in the intervention.
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Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
74 participants (actual)

Study arms

  • Experimental
    SMART Intervention

    Behavioral: Self-Monitoring Activity-restriction and Relaxation Training (SMART)

  • No intervention
    Usual Care

Interventions

  • BehavioralSelf-Monitoring Activity-restriction and Relaxation Training (SMART)

    SMART integrates real-time self-monitoring of symptoms and activities with interactive modules designed to increase self-efficacy through psychoeducation and training in problem solving/problem-focused coping strategies.

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What researchers measure

Primary outcomes

  1. Change in quality of life, as measured by the Pediatric Quality of Life Inventory (PedsQL)

    The PedsQL includes 23 items measuring physical, emotional, social, and school functioning.

    Time frame: From baseline to 4 weeks post-injury

Secondary outcomes

  1. Change in coping strategies, as measured by the Coping Strategies Inventory (CSI-S: Short Form)

    The CSI-S is a coping styles measure and has been used with other pediatric TBI samples. Adolescents rate how much they agree with 32-statements regarding different ways of coping with difficult situations on a 5-point Likert scale. Responses are then grouped into primary subscales reflecting eight different coping strategies (e.g., problem-solving, problem avoidance, social withdrawal, etc.).

    Time frame: From baseline to 4 weeks post-injury

  2. Change in self-efficacy for symptom management, as measured by the Self-Efficacy Scale (S-eS)

    This 2-item measure will be developed by the research team based on Bandura's self-efficacy theory. Adolescents will rate their level of confidence that they are able to maintain a plan to manage their symptoms each week

    Time frame: From baseline to 4 weeks post-injury

  3. Change in general functioning, as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS)

    PROMIS collects data from the adolescent participant and the parent about the impact a condition has on the adolescent's functioning.

    Time frame: From baseline to 4 weeks post-injury

  4. Change in health and behavioral symptoms, as measured by the Health and Behavior Inventory (HBI)

    The HBI is a 20-item questionnaire which includes a variety of cognitive, somatic, emotional, and behavioral symptoms requiring parents and adolescents to rate the frequency of occurrence of each symptom over the past week on a 4-point scale, ranging from "never" to "often."

    Time frame: From baseline to 4 weeks post-injury

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Study locations

1 site
  • Cincinnati Children's Hospital Medical Center
    Cincinnati, Ohio 45229, United States
07

References and documents

Study documents

  • Informed consent form · Oct 8, 2019

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: Undecided

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Registry details

Key details

Study ID
NCT03498495
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Collaborators
University of Cincinnati
Responsible party
Sponsor
First posted
Apr 13, 2018
Start date
May 12, 2019
Primary completion
Aug 31, 2020
Completion
Aug 31, 2020
Last update
Jul 10, 2023

Study contacts

Lynn Babcock, M.D.
principal investigator · Children's Hospital Medical Center, Cincinnati

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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