An interventional study of Nociception Coma Scale (NCS) in Minimally Conscious State and Vegetative State, sponsored by Hangzhou Normal University. Completed at 1 site in China. Open to participants aged 19 Years to 53 Years. Per ClinicalTrials.gov, last updated 2018-04-11.
Sponsored by Hangzhou Normal University · Not applicable, Interventional, and Diagnostic
The aim of this study was to translate the NCS from English into Chinese and determine the validity of this Chinese version.
The assessment and early diagnosis of pain is of great importance for pain management and treatment in patients with disorders of consciousness. The Nociception Coma Scale (- Revised) is only applicable to assess pain of DOC patients in international clinical setting. The aim of this study was to translate the NCS from English into Chinese and determine the validity of this Chinese version. To test internal reliability and inter-rater reliability, both rater A and rater B assess the perception of pain on day 1; and to obtain test-retest reliability, rater A assessed all patients repeatedly on day 2. 'Faces, Legs, Activity, Cry, Consolability' (FLACC) was used to analysis concurrent validity by rater A.
88 studies on the registry are indexed under Persistent Vegetative State; 20 are open to participants now.
This study's enrollment of 62 is above the median of 30 across 55 interventional studies indexed under Persistent Vegetative State.
Browse Persistent Vegetative State studies →Hangzhou Normal University is the lead sponsor of 22 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
patients with vegetative state lack awareness of self and environment even in the presence for eye-opening and sleep-wake cycles using CRS-R. The nailbed pressure was applied for 5 seconds and ended as soon as the behavioral response were captured. The raters recorded patients' behavioral responses using Nociception Coma Scale (NCS) during 10 seconds after each noxious stimulus.
Diagnostic Test: Nociception Coma Scale (NCS)
Patients with minimally conscious state display inconsistent, but reproducible and discernible signs of awareness using CRS-R. The nailbed pressure was applied for 5 seconds and ended as soon as the behavioral response were captured. The raters recorded patients' behavioral responses using Nociception Coma Scale (NCS) during 10 seconds after each noxious stimulus.
Diagnostic Test: Nociception Coma Scale (NCS)
Patients have been assessed with both the Nociception Coma Scale (NCS) and the FLACC.
Also known as: the Face Legs Activity Cry and Consolability (FLACC)
The level of perception of pain in DOC patients
This original NCS consists of four subscales to assess motor, verbal, visual and facial behavioral responses and each subscale score ranges from 0 to 3
Time frame: Within 2 days
This study is completed, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.
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Hangzhou Normal University