An observational study in Vegetative State and Minimally Conscious State, sponsored by Hangzhou Normal University. Completed at 1 site in China. Open to participants aged 21 Years to 61 Years. Per ClinicalTrials.gov, last updated 2018-04-10.
Sponsored by Hangzhou Normal University · Observational
The aim of the present study was to evaluated the neural effect of music on the cerebral activation in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) by using functional magnetic resonance imaging (fMRI).
Background: Sensory stimulations were used widely to evaluate the preserved cerebral functions for these patients with disorders of consciousness. Among these, the most alerting or common stimuli are probably familiar voice and music.
Objective: The aim of the present study was to evaluated the neural effect of music on the cerebral activation in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) by using functional magnetic resonance imaging (fMRI).
Methods: Eleven severely brain-damaged patients (6 UWS and 5 MCS) were assessed by functional magnetic resonance imaging while they were exposed under the condition of their personal music. To examine the prognostic value of these patients, longitudinal behavioral assessments were repeatedly conducted by means of the CRS-R after fMRI acquisition.
88 studies on the registry are indexed under Persistent Vegetative State; 20 are open to participants now.
This study's enrollment of 11 is below the median of 80 across 31 observational studies indexed under Persistent Vegetative State.
Browse Persistent Vegetative State studies →Hangzhou Normal University is the lead sponsor of 22 studies on the registry; 1 is open to participants now.
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patients with disorders of consciousness
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Exclusion Criteria:
patients with disorders of consciousness from several brain injury have been clinically classified into coma, unresponsive wakefulness syndrome and minimally conscious state. These patients were scaned by functional magnetic resonance imaging.
Diagnostic Test: functional magnetic resonance imaging
Patients with disorders of consciousness were assessed by functional magnetic resonance imaging while they were exposed under the condition of music.
Also known as: Coma Recovery Scale-Revised
Coma Recovery Scale-Revised
examine the prognostic value of these patients, longitudinal behavioral assessments were repeatedly conducted by means of the CRS-R after fMRI acquisition
Time frame: one to two years
Plan to share: Yes
This study is completed, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.
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Hangzhou Normal University