ClinicalTrials.gg
Status unknownNCT03484442Updated Mar 30, 2018

Multislice Computed Tomography Angiography in Acute Mesenteric Ischemia

An observational study in Mesenteric Ischemia, sponsored by Assiut University. Status unknown. Per ClinicalTrials.gov, last updated 2018-03-30.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified Mar 2018), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
30
Sex
All
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Study summary

Acute mesenteric ischemia is a life-threatening condition with high mortality. Acute mesenteric ischemia is responsible for fewer than one in 1000 hospital admissions, but its mortality rate ranges between 30% and 90% . Acute mesenteric ischemia is most commonly secondary to embolism followed by arterial thrombosis, non-occlusive ischemia, and less commonly venous thrombosis . Delay in diagnosis contributes to the continued high mortality rate. Early diagnosis and prompt effective treatment are essential to Correspondence to improve clinical outcomes

Read the detailed description

However, Acute mesenteric ischemia represents a major diagnostic challenge because of its varied presentations and multiple causes . Patients usually present with non-specific abdominal symptoms and laboratory findings, which leads to delayed diagnoses . Therefore, diagnostic imaging has emerged as one of the most crucial components in the diagnostic work-up of suspected

Recent technical advances have made computed tomography angiography the modality of choice in the setting of suspected Acute mesenteric ischemia.computed tomography angiography is a rapid and non-invasive diagnostic tool for assessing intestinal vasculature and bowel . computed tomography angiography allows early diagnosis and differentiation between occlusive and non-occlusive causes, which is important to direct therapeutic approach . Overall, combining vascular and bowel assessment results in a high diagnostic accuracy . A recent meta-analysis showed a sensitivity of 93% and a specificity of 96% . However, this meta analysis also showed that the prevalence of confirmed .Acute mesenteric ischemia is less than 25% among the patients referred to computed tomography angiograph in the setting of suspected Acute mesenteric ischemia .Knowledge of the prevalence and the demographic distribution of alternative diagnoses in the remaining three-fourths of patients without Acute mesenteric ischemia is important for appropriate patient care. computed tomography angiograph is considered to allow for a variety of acute alternative diagnoses, ensuring timely triage of these patients.

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Conditions studied

  • Mesenteric Ischemia

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In context

Mesenteric Ischemia

40 studies on the registry are indexed under Mesenteric Ischemia; 14 are open to participants now.

This study's planned enrollment of 30 is below the median of 154 across 26 observational studies indexed under Mesenteric Ischemia.

Browse Mesenteric Ischemia studies →

Lead sponsor

Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Clinically suspected acute mesentric ischemia based on physician evaluation Patients should be evaluated during 48 h of acute presentation

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Clinically suspected acute mesenteric ischemia based on physician evaluation Patients should be evaluated during 48 h of acute presentation

Exclusion criteria

Exclusion Criteria:

  • Renal Impairment
  • Known allergy to iodine contrast media.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
30 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. rate of diagnosis of Acute mesenteric ischemia

    number of patients accurately diagnosed acute mesenteric ischemia by multislice computed tomography angiography

    Time frame: 48 hours of presentation

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Ottinger LW. Mesenteric ischemia. N Engl J Med. 1982 Aug 26;307(9):535-7. doi: 10.1056/NEJM198208263070905. No abstract available. PubMed 7048095 ↗
  • Ozden N, Gurses B. Mesenteric ischemia in the elderly. Clin Geriatr Med. 2007 Nov;23(4):871-87, vii-viii. doi: 10.1016/j.cger.2007.07.001. PubMed 17923343 ↗
  • Herbert GS, Steele SR. Acute and chronic mesenteric ischemia. Surg Clin North Am. 2007 Oct;87(5):1115-34, ix. doi: 10.1016/j.suc.2007.07.016. PubMed 17936478 ↗
  • Paterno F, Longo WE. The etiology and pathogenesis of vascular disorders of the intestine. Radiol Clin North Am. 2008 Sep;46(5):877-85, v. doi: 10.1016/j.rcl.2008.06.005. PubMed 19103137 ↗
  • Reginelli A, Iacobellis F, Berritto D, Gagliardi G, Di Grezia G, Rossi M, Fonio P, Grassi R. Mesenteric ischemia: the importance of differential diagnosis for the surgeon. BMC Surg. 2013;13 Suppl 2(Suppl 2):S51. doi: 10.1186/1471-2482-13-S2-S51. Epub 2013 Oct 8. PubMed 24267670 ↗
  • Cudnik MT, Darbha S, Jones J, Macedo J, Stockton SW, Hiestand BC. The diagnosis of acute mesenteric ischemia: A systematic review and meta-analysis. Acad Emerg Med. 2013 Nov;20(11):1087-100. doi: 10.1111/acem.12254. PubMed 24238311 ↗
  • Martinez JP, Hogan GJ. Mesenteric ischemia. Emerg Med Clin North Am. 2004 Nov;22(4):909-28. doi: 10.1016/j.emc.2004.05.002. PubMed 15474776 ↗
  • Sise MJ. Acute mesenteric ischemia. Surg Clin North Am. 2014 Feb;94(1):165-81. doi: 10.1016/j.suc.2013.10.012. PubMed 24267504 ↗
  • Ofer A, Abadi S, Nitecki S, Karram T, Kogan I, Leiderman M, Shmulevsky P, Israelit S, Engel A. Multidetector CT angiography in the evaluation of acute mesenteric ischemia. Eur Radiol. 2009 Jan;19(1):24-30. doi: 10.1007/s00330-008-1124-5. Epub 2008 Aug 9. PubMed 18690454 ↗
  • Menke J. Diagnostic accuracy of multidetector CT in acute mesenteric ischemia: systematic review and meta-analysis. Radiology. 2010 Jul;256(1):93-101. doi: 10.1148/radiol.10091938. PubMed 20574087 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03484442
Lead sponsor
Assiut University
Responsible party
Basma Fawzy Mohammed (principle investigator, Assiut University) — Principal investigator
First posted
Mar 30, 2018
Start date
Apr 2018 (estimated)
Primary completion
Apr 2019 (estimated)
Completion
Jun 2019 (estimated)
Last update
Mar 30, 2018

Study contacts

Afaf Abdel-Qader Hasan Elmamlok, professor
Contact
afaf.kader@aun.edu.eg
02208843124
Abo-Elhassan Hasseib Mohammed, lecturer
Contact
abolhasan_96@aun.edu.eg
02201009562059

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.

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