An interventional study of Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system in Spinal Cord Injuries, Tetraplegia and Quadriplegia, sponsored by VA Office of Research and Development. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2026-02-20.
Sponsored by VA Office of Research and Development · Not applicable, Interventional, and Device feasibility
Among 76 studies in Spinal Cord Injuries by VA Office of Research and Development — 17 open to participants now, 18 under way, 1 of them phase 3. Spinal Cord Injuries · VA Office of Research and Development.
Among the 76 studies in Spinal Cord Injuries by VA Office of Research and Development, this one is the 67th largest by enrollment of the 69 interventional ones that give a count, is one of 2 that started in 2018, is one of 52 with no phase, and was the 39th registered.
2,025 studies on the registry are indexed under Spinal Cord Injuries; 537 are open to participants now.
Browse Spinal Cord Injuries studies →17 of the 76 studies in Spinal Cord Injuries by VA Office of Research and Development are open now, in 1 country. Recruiting first, the newest first:
VA Office of Research and Development · Sites in United States
Ages 18+
VA Office of Research and Development · Sites in United States
Ages 18+
VA Office of Research and Development · Sites in United States
Ages 18+
VA Office of Research and Development · Sites in United States
Ages 18–60
VA Office of Research and Development · Sites in United States
Ages 18+
By country, each count listing its studies:
Of the 375 Spinal Cord Injuries studies recruiting now, 166 (44%) set no upper age limit and 158 (42%) stop at 75 or younger; 41 take children under 18; 52 take healthy volunteers.
This study: all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
76 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 5 · Phase 2 13 · Phase 3 6 · Phase 4 1
First in 2003; this study’s year is marked. 2 started in 2018.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 1 is below the median of 24 across 1,633 interventional studies indexed under Spinal Cord Injuries.
Median enrollment 20 across the 69 interventional studies, 53 across the 7 observational. Of the 57 that completed or were terminated, 49 (86%) have results posted.
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VA Office of Research and Development is the lead sponsor of 1,771 studies on the registry; 392 are open to participants now.
Of its 213 completed or terminated interventional studies of FDA-regulated products, 185 (87%) have results posted.
10 of the studies in Spinal Cord Injuries by VA Office of Research and Development that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06130449VA Office of Research and DevelopmentTestosterone and Neural Function in Men With Spinal Cord Injury | 2026-12-31 |
| NCT05776030VA Office of Research and DevelopmentMulti-speed Ergonomic Wheelchair | 2026-12-31 |
| NCT05157282VA Office of Research and DevelopmentSpinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia | 2027-01-29 |
| NCT05553353VA Office of Research and DevelopmentDosing rTMS for Depression Post-SCI | 2027-04-15 |
| NCT05926596VA Office of Research and DevelopmentLeg Stretching Using an Exoskeleton on Demand for People With Spasticity | 2027-04-30 |
Add all 10 to your calendar (.ics) → With an account.
Among the 76 studies in Spinal Cord Injuries by VA Office of Research and Development, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study is for people who have a paralyzed arm and hand from a spinal cord injury, who have also received a recording electrode array in the brain as part of the BrainGate study. The study will look at the ability of these participants to control different grasping patterns of the hand, both in virtual reality and in his/her actual hand. Movement of the participant's hand is controlled by a functional electrical stimulation (FES) system, which involves small electrodes implanted in the arm, shoulder and hand that use small electrical currents to activate the appropriate muscles.
This work aims to advance Brain-Computer-Interfaces (BCls) to provide severely paralyzed persons a natural way of controlling Functional Electrical Stimulation (FES) neuroprostheses for restoring arm and dexterous hand movements. The prospect of using BCI technology for restoring arm and hand movements for reaching and grasping is based on the hypothesis that in a paralyzed human, there is a repeatable and understandable relationship between recordable brain activity and specific aspects of imagined arm movements. Many previous studies have attempted to understand the relationships between brain activity and arm and hand movements in able-bodied monkeys. Little is known about these same relationships in humans, and specifically within the context of trying to control an FES arm and complex hand system. This study will recruit persons who already have BCI and FES systems implanted to take advantage of the possibility of recording high resolution brain activity in human participants. Thus, from this study, we aim to gain a better understanding of how brain signals are related to specific aspects of arm and complex hand movements in humans with paralysis. Additionally, this study will test novel implementations of complex hand movement restoration in Veterans and other persons with chronic hand and arm paralysis.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Participants will be asked to think about holding different shaped objects, and the recorded cortical signal patterns will be decoded to match those grasp shapes
Device: Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system
Participants will be asked to think about holding different shaped objects, and the recorded cortical signal patterns will be decoded to match those grasp shapes
Ability to Form Appropriate Grasp Patterns
The success rate for achieving a series of specified grasp patterns will be calculated. This will be a percentage of the target grasp patterns successfully achieved. The reported outcome is an average of the outcomes (mean +/- standard deviation) over the full assessment period
Time frame: Outcomes were assessed on average every 3 months for the full time (4 years) that the participant was enrolled in the study.
| Milestone | Cortical Control of Grasp Patterns |
|---|---|
| Started | 1 |
| Completed | 1 |
| Not completed | 0 |
The success rate for achieving a series of specified grasp patterns will be calculated. This will be a percentage of the target grasp patterns successfully achieved. The reported outcome is an average of the outcomes (mean +/- standard deviation) over the full assessment period
| percentage of correct grasps formed | Cortical Control of Grasp Patterns |
|---|---|
| Ability to Form Appropriate Grasp Patterns | 78.75 ± 19.1 |
Collected over from enrollment until end of study, up to 48 months. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Cortical Control of Grasp Patterns | 0/1 (0%) | 0/1 (0%) | 0/1 (0%) |
| Age, Categorical(Participants) | Cortical Control of Grasp Patterns |
|---|---|
| <=18 years | 0 |
| Between 18 and 65 years | 1 |
| >=65 years | 0 |
| Sex: Female, Male(Participants) | Cortical Control of Grasp Patterns |
|---|---|
| Female | 0 |
| Male | 1 |
| Race (NIH/OMB)(Participants) | Cortical Control of Grasp Patterns |
|---|---|
| American Indian or Alaska Native | 0 |
| Asian | 0 |
| Native Hawaiian or Other Pacific Islander | 0 |
| Black or African American | 0 |
| White | 1 |
| More than one race | 0 |
| Unknown or Not Reported | 0 |
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No — We will not be sharing individual participant data.
Ran from Jun 2018 to primary completion in Sep 2023, 63 months.
Results were first posted in Feb 2026, 2 years 4 months after primary completion.
Of 790 non-industry interventional studies with no phase under Spinal Cord Injuries, half reached primary completion within 37 months of starting (the median), counting those still running; a quarter within 18 and three quarters within 65. This study's 63 months is above that.
Counting every sponsor, half of 839 studies reached it within 36 months; a quarter within 17 and three quarters within 64.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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