An interventional study of transcranial direct current stimulation in Consciousness Disorder and Transcranial Direct Current Stimulation, sponsored by First Affiliated Hospital of Zhejiang University. Withdrawn at 1 site in China. Open to male participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-10-23.
Sponsored by First Affiliated Hospital of Zhejiang University · Not applicable, Interventional, and Treatment
test
Neurostimulation techniques such as deep brain stimulation (DBS) and spinal cord stimulation (SCS) have been used to treat DOC. Although these techniques have been shown to increase patient response, there are still some limitations. For example, DBS requires craniotomy and may increase the risk of intracranial hemorrhage and infection. In addition, the complexity and cost of these technologies also limit their potential applications.
Patients with DOC: VS and MCS (the cause of unification is: traumatic brain injury, the course of more than 1 month, not more than 1 year ; age 18-65; Past history without a mental disorder; No previous alcohol or substance abuse; No epilepsy or frequent spontaneous movement; No benzodiazepines; No moderate or severe hydrocephalus, All patients were right handed.
Exclusion Criteria:
Exclusion of organic heart disease, such as sinus bradycardia, arrhythmia; exclusion of patients with intracranial metal devices, pacemakers or any other device.
Direct current was applied by a battery-driven constant current stimulator using saline-soaked surface sponge electrodes (7×5 cm) with the anode positioned over the left dorsolateral prefrontal cortex (F3 according to the 10-20 international system for EEG placement) and the cathode placed over the right supraorbital region. During real tDCS, the current was increased to 2 mA from the onset of stimulation and applied for 20 minutes.
Device: transcranial direct current stimulation
the treatment of transcranial direct current stimulation
improvement of CRS-R
test
Time frame: 7 days
Plan to share: Undecided
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This study is withdrawn, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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First Affiliated Hospital of Zhejiang University