An observational study in High-resolution Magnetic Resonance Imaging; Disorders of Consciousness, sponsored by First Affiliated Hospital of Zhejiang University. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2018-03-23.
Sponsored by First Affiliated Hospital of Zhejiang University · Observational
In this study, high-resolution brain functional magnetic resonance imaging (MRI) was used to evaluate the differences in brain structure and brain function network between patients with different degrees of disturbance of cognition and healthy controls by means of cohort follow-up and control study. The changes of patients' The dynamic changes of learning, to explore its clinical value as an early diagnosis. Combined with neurobehavioral scales and high-resolution brain structure, functional magnetic resonance imaging data to assess the brain structure, functional characteristics and consciousness of patients with impaired consciousness, and initially establish awareness of patients with recovery of consciousness Predictable imaging signs. Twenty eligible controls, 20 VS patients, and 20 MCS patients will be considered for inclusion in the inclusion / exclusion criteria. Informed consent will be obtained as required before starting any registration process.
These patients were admitted to the Department of Rehabilitation at Hangzhou Hospital of Zhejiang CAPR.
(1) no use of centrally acting drugs, (2) no use of neuromuscular function blockers and no sedation within the prior 24 h, (3) periods of eye opening indicating a preserved sleep-wake cycle, and (4) a diagnosis of VS or MCS established according to internationally established criteria
Exclusion Criteria:
Magnetic resonance contraindications
Diffusion magnetic resonance imaging analysis
The color-coding of tractography pathways in was determined for a visualization purpose. The color-coding of tractography pathways was based on FA values.
Time frame: Three months
This study is status unknown, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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First Affiliated Hospital of Zhejiang University