An observational study in Bariatric Surgery, Sleeve Gastrectomy and Obesity, sponsored by Brigham and Women's Hospital. Completed at 1 site in United States. Open to participants aged 21 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by Brigham and Women's Hospital · Observational
The purpose of the study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.
The obesity epidemic is a major public health concern with a significant economic burden in the USA. Bariatric surgery is the most effective and durable weight loss treatment, with long-term cardiometabolic health benefits. Among different types of bariatric procedures, sleeve gastrectomy (SG) has become the most commonly performed in USA. While SG is expected to result in a 50-60% excess weight loss, inter-individual differences in weight loss are large and approximately 25% of patients can be considered poor weight-loss responders who either do not lose a substantial amount of weight or regain the lost weight afterwards. The mechanisms underlying this clinical variation remain unknown and interventions to improve on these outcomes critically lacking. Of interest, altered daily dietary habits are experienced by a substantial proportion of bariatric surgery candidates, raising the question whether such alterations may contribute to inter-individual differences in weight loss success. Therefore, the purpose of this study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.
11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.
This study's enrollment of 291 is above the median of 114 across 2,154 observational studies indexed under Obesity.
Browse Obesity studies →Brigham and Women's Hospital is the lead sponsor of 1,267 studies on the registry; 228 are open to participants now.
Of its 116 completed or terminated interventional studies of FDA-regulated products, 65 (56%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients electing to undergo sleeve gastrectomy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Patients electing to undergo sleeve gastrectomy will monitor their dietary habits.
Other: Dietary habits
Sleeve gastrectomy patients will be asked to monitor dietary habits before surgery and at 2, 6, and 12 months after surgery.
Percentage Change in Weight at 1-year Post-surgery
Percentage change in body weight at one year was calculated as \[(weight at one year - baseline weight)/baseline weight\] × 100. Negative values indicate weight loss, whereas positive values indicate weight gain.
Time frame: Baseline and one year
| Milestone | Sleeve Gastrectomy Patients |
|---|---|
| Started | 291 |
| Completed | 125 |
| Not completed | 166 |
Percentage change in body weight at one year was calculated as \[(weight at one year - baseline weight)/baseline weight\] × 100. Negative values indicate weight loss, whereas positive values indicate weight gain.
| percentage change | Sleeve Gastrectomy Patients |
|---|---|
| Percentage Change in Weight at 1-year Post-surgery | -26.6 ± 8.3 |
Collected over from enrollment until up to 14 months after their surgical date. Non-serious events are listed at a 5% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Sleeve Gastrectomy Patients | 0/291 (0%) | 0/291 (0%) | 0/291 (0%) |
Included participants who completed the study
| Age, Continuous(years) | Sleeve Gastrectomy Patients |
|---|---|
| Mean | 40.9 ± 11.2 |
| Sex: Female, Male(Participants) | Sleeve Gastrectomy Patients |
|---|---|
| Female | 103 |
| Male | 22 |
| Race (NIH/OMB)(Participants) | Sleeve Gastrectomy Patients |
|---|---|
| American Indian or Alaska Native | 1 |
| Asian | 1 |
| Native Hawaiian or Other Pacific Islander | 0 |
| Black or African American | 12 |
| White | 94 |
| More than one race | 3 |
| Unknown or Not Reported | 14 |
| Ethnicity (NIH/OMB)(Participants) | Sleeve Gastrectomy Patients |
|---|---|
| Hispanic or Latino | 22 |
| Not Hispanic or Latino | 101 |
| Unknown or Not Reported | 2 |
| Body mass index(kilograms per square meter) | Sleeve Gastrectomy Patients |
|---|---|
| Mean | 46.1 ± 7.5 |
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Dec 2018 to primary completion in Mar 2025, 74 months.
Results were first posted in Nov 2026, 1 year 8 months after primary completion.
Of 791 non-industry observational studies under Obesity, half reached primary completion within 40 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 106. This study's 74 months is above that.
Counting every sponsor, half of 836 studies reached it within 39 months; a quarter within 17 and three quarters within 96.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Brigham and Women's Hospital →