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CompletedNCT03468660Updated Mar 14, 2022

Auditory Temporal Processes in Aging

An interventional study of Auditory training with feedback and Listening paradigm with no feedback in Auditory Perceptual Disorders and Aging Problems, sponsored by University of Maryland, College Park. Completed at 1 site in United States. Open to participants aged 18 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-03-14.

Sponsored by University of Maryland, College Park · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
82
Allocation
Non-randomized
Ages
18 Years to 85 Years
Sex
All
01

Study summary

Older people experience great difficulty understanding speech, especially accented English, and this problem is expected to increase with the influx of immigrants who provide services to the elderly population. The research examines the underlying factors that contribute to older listeners' difficulty understanding accented speech, including those associated with age-related hearing loss, changes in processing in auditory pathways in the brain, and general cognitive decline. The investigation also evaluates the efficacy of training strategies to improve understanding of accented English by older people. Outcomes of this research are expected to improve communication between senior citizens and those with whom they interact daily, and thereby improve quality of life for the older segment of the Nation's population.

Read the detailed description

This research program in speech perception and auditory psychophysics examines the hypothesis that many of the predominant difficulties in speech understanding of elderly listeners are related to underlying problems in auditory temporal processing. One form of degraded speech that is particularly difficult for elderly listeners to perceive is accented English. Alterations of speech stress and timing with accent may be viewed as a form of degradation in temporal aspects of speech prosody, and this type of temporal distortion is the focus of investigation in the next project period. Moreover, psychoacoustic results demonstrate that large age-related difficulties in temporal processing exist for the perception of auditory tempo and rhythmic characteristics of sequential stimulus patterns featuring a stressed tone. Listener processing difficulty could be attributed to peripheral and/or central processing mechanisms, as well as various cognitive factors, including the degree of familiarity with prosodic features of different native languages. The project examines the relative contribution of peripheral hearing impairment, type of stimulus temporal complexity and cognitive demand, and the linguistic background experience of listeners on the processing of temporal prosody cues in speech and non-speech stimulus patterns. The project associated with this clinical trial examines the efficacy of auditory training paradigms with stimuli that feature temporal contrasts for improving perception of accented English and non-speech sequences by older people. The research described in this application seeks to address one goal outlined by the National Institute on Aging: to develop effective interventions to maintain health and function and prevent or reduce the burden of age-related diseases, disorders, and disabilities. The approach in this research program involves (a) an assessment of the problems encountered in daily activities by the elderly population, (b) an analysis of specific task demands in relation to individual capabilities, and (c) basic research on sensory and perceptual changes with age and on the ameliorating effects of emerging technologies (including rehabilitation). This three-dimensional approach is expected to further progress toward improving communication and health-related quality of life for senior citizens.

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Conditions studied

  • Auditory Perceptual Disorders
  • Aging Problems

Keywords

  • Accented speech perception
03

Who can participate

Ages eligible
18 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age and hearing sensitivity:
  • Younger listeners (18-40 years) with normal hearing;
  • Older listeners (65-80 years) with normal hearing;
  • Older listeners (65-80 years) with bilateral, mild-to-moderate sensorineural hearing loss.
  • High School Diploma,
  • native speaker of English (based on self-report)
  • normal middle-ear function (based on tympanometry)
  • normal cognitive function (based on score on Montreal Cognitive Assessment)
  • good-to-excellent word recognition scores (based on Northwestern University Test # 6 word recognition scores presented in quiet at suprathreshold levels).

Exclusion criteria

Exclusion Criteria:

  • non-native speaker of English,
  • motor and/or speech disorders that prevent participant from providing a time-locked response,
  • presence of middle ear disease or conductive hearing loss,
  • presence of severe or profound hearing loss,
  • presence of poor word recognition scores,
  • cognitive impairment.
04

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
82 participants (actual)

Study arms

  • Experimental
    Experimental group

    Auditory training with feedback

    Behavioral: Auditory training with feedback

  • No intervention
    Passive control group

    Pre-post testing only; no training

  • Active comparator
    Active Control group

    Listening task with no feeback

    Behavioral: Listening paradigm with no feedback

Interventions

  • BehavioralAuditory training with feedback

    Experimental group receives phoneme-level and sentence-level training with feedback

  • BehavioralListening paradigm with no feedback

    Active controls listen to acoustic stimuli with no feedback

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What researchers measure

Primary outcomes

  1. Recognition of accented speech stimuli used for training

    Scale: Accented words (n = 160) and accented sentences (n = 35 sentences) used in training; construct: measures percent correct recognition; minimum score = 0%, maximum score = 100%. Higher values are considered a better outcome

    Time frame: 1 day

Secondary outcomes

  1. Generalization of benefit in recognizing accented speech

    Scale: Accented words (n = 48) and accented sentences (n = 10 sentences) with new talker and speech stimuli not used in training. Construct measures percent correct recognition score for accented words and sentences not used in training, with minimum = 0% and maximum = 100%. Better performance is a higher percent correct score.

    Time frame: 1 day

  2. Retention of benefit in recognizing accented speech

    Scale: Accented words (n = 64) and accented sentences (n = 90). For words: familiar words and familiar talkers (n = 32) and new talkers and new words (n = 32). For sentences: familiar talkers and words (used in training; n = 40), new talkers and new lists not heard before (n = 20), and talkers and sentences heard before but not used in training (n = 30). Construct: percent correct recognition for trained talker and lists, new talkers and new stimuli, and familiar talkers and lists not used in training. Construct: percent correct recognition (min = 0%, max = 100%), with better performance a higher recognition score.

    Time frame: through study completion, an average of two weeks

06

Study locations

1 site
  • University of Maryland
    College Park, Maryland 20742, United States
07

References and documents

Publications

  • Gordon-Salant S, Yeni-Komshian GH, Bieber RE, Jara Ureta DA, Freund MS, Fitzgibbons PJ. Effects of Listener Age and Native Language Experience on Recognition of Accented and Unaccented English Words. J Speech Lang Hear Res. 2019 Apr 26;62(4S):1131-1143. doi: 10.1044/2018_JSLHR-H-ASCC7-18-0122. PubMed 31026190 ↗
  • Bieber RE, Yeni-Komshian GH, Freund MS, Fitzgibbons PJ, Gordon-Salant S. Effects of listener age and native language on perception of accented and unaccented sentences. J Acoust Soc Am. 2018 Dec;144(6):3191. doi: 10.1121/1.5081711. PubMed 30599683 ↗
  • Bieber RE, Gordon-Salant S. Adaptation to novel foreign-accented speech and retention of benefit following training: Influence of aging and hearing loss. J Acoust Soc Am. 2017 Apr;141(4):2800. doi: 10.1121/1.4980063. PubMed 28464671 ↗
  • Fitzgibbons PJ, Gordon-Salant S. Age effects in discrimination of intervals within accented tone sequences differing in accent type and sequence presentation rate. J Acoust Soc Am. 2016 Nov;140(5):3819. doi: 10.1121/1.4967512. PubMed 27908085 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Pickett EJ, Fitzgibbons PJ. Perception of contrastive bi-syllabic lexical stress in unaccented and accented words by younger and older listeners. J Acoust Soc Am. 2016 Mar;139(3):1132-48. doi: 10.1121/1.4943557. PubMed 27036250 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Cohen JI. Effects of age and hearing loss on recognition of unaccented and accented multisyllabic words. J Acoust Soc Am. 2015 Feb;137(2):884-97. doi: 10.1121/1.4906270. PubMed 25698021 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Cohen JI, Waldroup C. Recognition of accented and unaccented speech in different maskers by younger and older listeners. J Acoust Soc Am. 2013 Jul;134(1):618-27. doi: 10.1121/1.4807817. PubMed 23862836 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ. Recognition of accented English in quiet and noise by younger and older listeners. J Acoust Soc Am. 2010 Nov;128(5):3152-60. doi: 10.1121/1.3495940. PubMed 21110610 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Schurman J. Short-term adaptation to accented English by younger and older adults. J Acoust Soc Am. 2010 Oct;128(4):EL200-4. doi: 10.1121/1.3486199. PubMed 20968326 ↗
  • Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ. Recognition of accented English in quiet by younger normal-hearing listeners and older listeners with normal-hearing and hearing loss. J Acoust Soc Am. 2010 Jul;128(1):444-55. doi: 10.1121/1.3397409. PubMed 20649238 ↗
  • Fitzgibbons PJ, Gordon-Salant S. Age-related differences in discrimination of temporal intervals in accented tone sequences. Hear Res. 2010 Jun 1;264(1-2):41-7. doi: 10.1016/j.heares.2009.11.008. Epub 2009 Dec 3. PubMed 19931608 ↗

Individual participant data

Plan to share: No

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Registry details

Key details

Study ID
NCT03468660
Lead sponsor
University of Maryland, College Park
Responsible party
Sandra Gordon Salant (Professor, University of Maryland, College Park) — Principal investigator
First posted
Mar 16, 2018
Start date
Jan 18, 2018
Primary completion
Jun 30, 2020
Completion
Jun 30, 2020
Last update
Mar 14, 2022

Study contacts

Sandra Gordon-Salant, Ph.D.
principal investigator · University of Maryland

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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