An observational study in Proton Pump Inhibitor, sponsored by Fondation Hôpital Saint-Joseph. Completed at 1 site in France. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2019-08-06.
Sponsored by Fondation Hôpital Saint-Joseph · Observational
Proton pump inhibitor are frequently used and are short term well tolerated ; but few studies show there are adverse event in long term prescription like fracture or pulmonary infection to Clostridum difficile. The fact is that multi medication in old patient increase the iatrogenic risk and decrease the medication compliance. The Proton pump inhibitor (PPI)are overused in this patient category.Several studies suggest the existence of a rebound effect when people were treated more than 8 weeks ; this effect seems to appear around 14 days after with hyperacidity symptoms.
But there are no studies about old patient. So in this context the aim of the study is to evaluate the prevalence of rebound effect occurence after the end of PPI 8 weeks treatment.
Patient admitted in Leopold Bellan post acute an rehabilitation institution.
Exclusion Criteria:
number aof antacids treatment after PPI stop
Number of antacids used
Time frame: Day 14 after end of treatment
This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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Fondation Hôpital Saint-Joseph