An interventional study of Exercise in Chronic Disease, Lung Diseases, Obstructive and Respiratory Disease, sponsored by University of Zurich. Completed at 5 sites in Switzerland. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2021-12-27.
Sponsored by University of Zurich · Not applicable, Interventional, and Other
Among 39 studies in Pulmonary Disease, Chronic Obstructive by University of Zurich — 1 open to participants now, 3 under way, none of them phase 3. Pulmonary Disease, Chronic Obstructive · University of Zurich.
Among the 39 studies in Pulmonary Disease, Chronic Obstructive by University of Zurich, this one is the 8th largest by enrollment of the 33 interventional ones that give a count, is one of 3 that started in 2018, is one of 17 with no phase, and was the 23rd registered.
5,520 studies on the registry are indexed under Pulmonary Disease, Chronic Obstructive; 856 are open to participants now.
Browse Pulmonary Disease, Chronic Obstructive studies →1 of the 39 studies in Pulmonary Disease, Chronic Obstructive by University of Zurich is open now, in 1 country. Recruiting first, the newest first:
University of Zurich · Sites in Switzerland
By country, each count listing its studies:
Of the 555 Pulmonary Disease, Chronic Obstructive studies recruiting now, 305 (55%) set no upper age limit and 82 (15%) stop at 75 or younger; 29 take children under 18; 87 take healthy volunteers.
This study: 40 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
39 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 3 started in 2018.
This study's enrollment of 123 is above the median of 62 across 3,839 interventional studies indexed under Pulmonary Disease, Chronic Obstructive.
Median enrollment 69 across the 33 interventional studies, 158 across the 6 observational. Of the 32 that completed or were terminated, 0 (0%) have results posted.
This tab as a report to print or save as PDF → With an account.
University of Zurich is the lead sponsor of 1,049 studies on the registry; 133 are open to participants now.
1 of the studies in Pulmonary Disease, Chronic Obstructive by University of Zurich that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT05163600University of ZurichThe Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR) | 2026-12-31 |
Among the 39 studies in Pulmonary Disease, Chronic Obstructive by University of Zurich, from their registry updates:
Nothing recorded among them since 2026-09-25.
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The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who have completed a pulmonary rehabilitation.
Exercise training is an important component of the management of chronic obstructive pulmonary disease (COPD) and numerous trials have shown large improvements in health-related quality of life (HRQoL) and exercise capacity in persons with COPD. However, the great majority of patients who would benefit from pulmonary rehabilitation (PR) never follow such a program. Moreover, many COPD patients are either not instructed to exercise at all or fail to adhere to exercise training at home after completing pulmonary rehabilitation.
This study evaluates an exercise training program that requires minimal equipment (i.e., only a chair and elastic bands) and can be easily implemented long-term in the patient's home-setting.
5,520 studies on the registry are indexed under Pulmonary Disease, Chronic Obstructive; 856 are open to participants now.
This study's enrollment of 123 is above the median of 62 across 3,839 interventional studies indexed under Pulmonary Disease, Chronic Obstructive.
Browse Pulmonary Disease, Chronic Obstructive studies →University of Zurich is the lead sponsor of 1,049 studies on the registry; 133 are open to participants now.
Compared within Pulmonary Disease, Chronic Obstructive, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Chronic Disease. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
From a breathing test (spirometry): how much air you can blow out in the first second. Often given as a percentage of what is expected for your age, height and sex.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
FEV1
From a breathing test (spirometry): how much air you can blow out in the first second. Often given as a percentage of what is expected for your age, height and sex.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Home-based, minimal equipment exercise training program.
Behavioral: Exercise
Usual care (study participation does not have any impact on regular treatment or treatment decisions, including participation in other exercise training programs or rehabilitation programs)
Home-based exercise training program that requires only minimal equipment, and is individually adaptable to the participant's exercise level (6 times per week; 15-20 min; 38 exercise cards and one interactive training agenda booklet). After randomization, a health care professional (HOMEX coach) will visit the intervention group participants at their home to set up the training location, to instruct the exercises and to establish individualized goals. Follow-up visits are planned after 3 and 8-9 weeks. Regular telephone calls will be conducted by the same HOMEX coach to motivate the patients, to discuss training progress and concrete benefits and barriers, and to adapt goals and the training program. Additional intervention elements are that a relative or friend is involved as a "sparring" partner to support the participant. The general practitioner is informed about the participation of his/her patient in the intervention.
Dyspnea
Dyspnea domain of the Chronic Respiratory Questionnaire (CRQ); 5 questions; 7-point Likert-type scale ranging from 1 (most severe dyspnea) to 7 (no dyspnea)
Time frame: Change from baseline to 12 months
Dyspnea
Dyspnea domain of the Chronic Respiratory Questionnaire (CRQ); 5 questions; 7-point Likert-type scale ranging from 1 (most severe dyspnea) to 7 (no dyspnea)
Time frame: Change from baseline to 3, 6 and 12 months
Exercise capacity
Six-Minute Walk Test (walk distance) and 1-min Sit-to-Stand Test (number of repetitions)
Time frame: Change from baseline to 12 months
Health-related quality of life
Chronic Respiratory Questionnaires (CRQ): Fatigue, emotional function, mastery domain and EuroQoL (EQ-5D-5L): 5 Dimensions - Mobility, self-care, usual activities, pain/discomfort, anxiety/depression including 1 item each with 5 levels
Time frame: Change from baseline to 12 months
Health status
Visual analogue scale "Feeling thermometer" (0-100 scale; 0= "worst health you can imagine"; 100="best health you can imagine")
Time frame: Change from baseline to 12 months
Exacerbations
Event based, patient reported
Time frame: During entire study, assessed at 12 months
Symptoms
Questionnaire, COPD Assessment Test
Time frame: Change from baseline to 12 months
Compliance to the exercise training program
Percentage of fulfilled training sessions based on training diaries
Time frame: Assessed daily by intervention group participants during 12 months
Satisfaction with the exercise training program
Questionnaire (Likert-Type scales)
Time frame: From baseline to 12 months
Experience with the exercise training program
Semi-structured interview
Time frame: From baseline to 12 months (assessed at 12 months)
Health professionals' feedback
Semi-structured interview
Time frame: Assessed at 12 months
Cost effectiveness
Questionnaire: cost per quality-adjusted life year
Time frame: From baseline to 12 months (assessed at 3, 6, 12 months)
Plan to share: Undecided
Ran from Jan 2018 to primary completion in Mar 2020, 25 months.
Of 1,094 non-industry interventional studies with no phase under Pulmonary Disease, Chronic Obstructive, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 25 months is above that.
Counting every sponsor, half of 1,181 studies reached it within 22 months; a quarter within 10 and three quarters within 39.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
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Pulmonary Disease, Chronic Obstructive →