An interventional study of Super Beets and Beetroot powder in Vasodilation, Blood Pressure and Active Hyperemia, sponsored by University of Iowa. Completed at 1 site in United States. Open to participants aged 60 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-09.
Sponsored by University of Iowa · Not applicable, Interventional, and Basic science
Among 148 studies in Aneurysm with a site in United States — 31 open to participants now, 38 under way, none of them phase 3. Aneurysm · United States.
Among the 148 studies in Aneurysm with a site in United States, this one is the 97th largest by enrollment of the 111 interventional ones, is one of 7 that started in 2017, is one of 66 with no phase, and was the 101st registered.
381 studies on the registry are indexed under Aneurysm; 78 are open to participants now.
This study's enrollment of 10 is below the median of 46 across 235 interventional studies indexed under Aneurysm.
Browse Aneurysm studies →31 of the 148 studies in Aneurysm with a site in United States are open now, in 12 countries. Each count lists the studies.
Of the 67 Aneurysm studies recruiting now, 42 (63%) set no upper age limit and 7 (10%) stop at 75 or younger; 6 take children under 18; 9 take healthy volunteers.
This study: 60 Years to 80 Years · all sexes · healthy volunteers too.
The full table on the hub →148 studies; the count open now beside each. This study's row is marked.
First in 1997; this study’s year is marked. 7 started in 2017.
Median enrollment 60 across the 111 interventional studies, 114 across the 33 observational. Of the 91 that completed or were terminated, 35 (38%) have results posted.
46 of 148 have an industry lead sponsor. The 10 most frequent:
University of Iowa is the lead sponsor of 279 studies on the registry; 33 are open to participants now.
Of its 45 completed or terminated interventional studies of FDA-regulated products, 40 (89%) have results posted.
University of Iowa has 3 studies filed under Aneurysm — fewer than ten, so there is no comparison to draw.
11 of the studies in Aneurysm with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07116408Wright State UniversityIntranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage | 2026-11 |
| NCT06290713University of FloridaVasodilator and Exercise Study for DMD (VASO-REx) | 2026-11 |
| NCT06417177University of Missouri-ColumbiaImpact of Early Aging and Menopause on the Vascular Responses to Hypoxia | 2026-12 |
| NCT05522075The University of Texas at ArlingtonReducing Blood Pressure in Mid-life Adult Binge Drinkers | 2026-12-31 |
| NCT06793059Jacobs instituteEvaluation of Flow Diverter Technology Device for Intracranial Aneurysm (SHIELD) | 2027-01-01 |
Among the 148 studies in Aneurysm with a site in United States, from their registry updates:
The main purpose of this study is to evaluate the effects of an acute dose of dietary nitrate in the form of beetroot juice on skeletal muscle blood flow in response to dynamic knee extension exercise in healthy older adults. All subjects will receive active (rich in dietary nitrate) or placebo (devoid of nitrate) supplementation.
Dietary nitrate (beetroot juice) is reduced to nitrite and nitric oxide within the digestive system of humans. Nitric oxide exerts potent vasodilator effects, which have been shown to reduce blood pressure and enhance exercise economy in humans. This pressure reducing effect may have implications within the regulation of blood flow during dynamic exercise in older adults.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Dietary nitrate in the form of beetroot powder (10g) mixed in water will be administered acutely
Dietary Supplement: Super Beets · Dietary Supplement: Beetroot powder
Beetroot powder devoid of nitrate (10g) will be mixed in water and administered acutely
Dietary Supplement: Super Beets · Dietary Supplement: Beetroot powder
Nitrate rich beetroot powder (10g) acutely
Nitrate devoid beetroot powder (10g) acutely
Change in Skeletal Muscle Blood Flow within the Leg via Doppler Ultrasound
Leg blood flow via Doppler ultrasound examined during dynamic knee extension exercise. Change in blood flow in response to dynamic knee exercise will be measured to examine the influence of dietary nitrate.
Time frame: Pre and 2 hours post acute ingestion of dietary nitrate and placebo with at least 5 days of separation between visits.
Ran from Oct 2017 to primary completion in Feb 2018, 3 months.
Of 45 non-industry interventional studies with no phase under Aneurysm, half reached primary completion within 75 months of starting (the median), counting those still running; a quarter within 12. This study's 3 months is below that.
Counting every sponsor, half of 83 studies reached it within 45 months; a quarter within 19 and three quarters within 134.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Beet