ClinicalTrials.gg
TerminatedNCT03454191Updated Aug 22, 2024

Efficacy of Erector Spinae Plane Block for Postoperative Analgesia in Adult Patients Undergoing Thoracoscopy

An interventional study of Erector spinae plane block and No injection in Pain, Postoperative, sponsored by Eric Albrecht. Terminated at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-08-22.

Sponsored by Eric Albrecht · Not applicable, Interventional, and Treatment

Why this study was terminated
Recruitment stopped due to lack of research assistant
Phase
Not applicable
Study type
Interventional
Enrollment
10
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 56 studies in Pain, Postoperative with a site in Switzerland — 12 open to participants now, 12 under way, none of them phase 3. Pain, Postoperative · Switzerland.

Enrollment
47th of 47
10 · median 100
Started
2018
with 10 others
No phase
29 of 56
9 open now
Registered
20th of 56
by date
Lead sponsor
3 of 56
Eric Albrecht

Among the 56 studies in Pain, Postoperative with a site in Switzerland, this one is the 47th largest by enrollment of the 47 interventional ones, is one of 11 that started in 2018, is one of 29 with no phase, and was the 20th registered.

By phase

56 studies; the count open now beside each. This study's row is marked.

No phasethis study29 · 9 open
Phase 411 · 0 open
Observational9 · 3 open
Phase 34 · 0 open
Phase 22 · 0 open
Phase 2/31 · 0 open

By the year they started

First in 2004; this study’s year is marked. 11 started in 2018.

Size and results

Median enrollment 100 across the 47 interventional studies, 355 across the 9 observational. Of the 42 that completed or were terminated, 4 (10%) have results posted.

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02

Study summary

The erector spinae plane block has been recently described as an effective analgesic postoperative pain treatment in case reports. It consists of injecting local anaesthetics below the erector spinae muscle, at the level of the transverse processes, in order to anaesthetize the thoracic roots coming out from the spinal cord. However, the analgesic efficacy has never been demonstrated in a randomized controlled trial. Therefore, the objective of this study is to investigate the analgesic benefit of this block on patients scheduled for thoracoscopy.

03

Conditions studied

  • Pain, Postoperative

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04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients scheduled for thoracoscopy
  • physical status I-III

Exclusion criteria

Exclusion Criteria:

  • allergy to local anaesthetics
  • other to peripheral nerve blocks
  • patients suffering from chronic pain condition
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
10 participants (actual)

Study arms

  • Experimental
    Erector spinae plane block

    Procedure: Erector spinae plane block

  • Placebo comparator
    Placebo

    Procedure: No injection

Interventions

  • ProcedureErector spinae plane block

    Injection of local anaesthetics below the erector spinae muscle after induction of anaesthesia

  • ProcedureNo injection

    No injection

06

What researchers measure

Primary outcomes

  1. IV morphine consumption

    mg

    Time frame: 24 postoperative hours

Secondary outcomes

  1. IV morphine consumption

    mg

    Time frame: 2 postoperative hours

  2. IV morphine consumption

    mg

    Time frame: 48 postoperative hours

  3. Pain scores

    Visual analog scale, 0-10

    Time frame: 2, 24, 24 postoperative hours

  4. Chronic pain scores

    Visual analog scale, 0-10

    Time frame: 3 and 6 postoperative months

  5. Forced vital capacity

    L

    Time frame: 24 and 48 postoperative hours

07

Study locations

1 site
  • Department of Anesthesia, Centre Hospitalier Universitaire Vaudois and University of Lausanne
    Lausanne, Vaud 1011, Switzerland
08

References and documents

Individual participant data

Plan to share: Yes

Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Feb 2018 to primary completion in Oct 2023, 68 months.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 27, 2018
First posted
Mar 5, 2018
StartActual
Feb 1, 2018
Primary completionActual
Oct 1, 2023
CompletionActual
Oct 1, 2023
Last update
Aug 22, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 22, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03454191
Lead sponsor
Eric Albrecht
Responsible party
Eric Albrecht (Program director of regional anaesthesia, Centre Hospitalier Universitaire Vaudois) — Sponsor-investigator
First posted
Mar 5, 2018
Start date
Feb 1, 2018
Primary completion
Oct 1, 2023
Completion
Oct 1, 2023
Last update
Aug 22, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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