An interventional study of Thoracic paravertebral block(TPVB) group in Comparison of Thoracic Paravertebral Block to Serratus Anterior Plane Block in Breast Surgery, sponsored by Cairo University. Completed at 2 sites in Egypt. Open to female participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-03-16.
Sponsored by Cairo University · Not applicable, Interventional, and Supportive care
The investigators hypothesize that the analgesic efficacy of ultrasound-guided serratus anterior plane block will provide better analgesia with fewer complications in comparison to ultrasound guided thoracic paravertebral block
•The blocks techniques:
Exclusion Criteria:
These patients will receive single ipsilateral Ultrasound TPVB which performed with the patient in the sitting position at the level of the T4 with the probe in a vertical position 2.5-3 cm lateral to the midline. The midpoint of the transducer is to be placed in a longitudinal paramedian plane between two transverse processes which visualized with the superior costo-transverse ligament and the pleura visible in between . After this, 15-20 cc of bupivacaine 0.25% will be injected
Procedure: Thoracic paravertebral block(TPVB) group
These patients will receive serratus anterior plane block. The block will be performed while the patient is in the supine position by using a linear Ultrasound probe of high frequency (6-13 MHz) after sheathing. The probe will be placed over the mid-clavicular region of the thoracic cage in a sagittal plane. The ribs will be counted inferiorly and laterally, until the 5th rib is identified in the midaxillary line. The latissimus dorsi (superficial and posterior) , teres major (superior) and serratus muscles (deep and inferior) will be then easily identifiable by U/S overlying the fifth rib.
Procedure: Thoracic paravertebral block(TPVB) group
Thoracic paravertebral block group (TPVB) group: The midpoint of the transducer is to be placed in a longitudinal paramedian plane between two transverse processes.Tuohy needle will be introduced in a cephalad direction. The tip of the needle will be advanced under direct visualization until it pierces the superior costo-transverse ligament. When the needle tip is located immediately above the pleura, the needle is aspirated to confirm the absence of blood or air. Serratus anterior plane block group (SAP) group: The US probe will be placed over the mid-clavicular region of the thoracic cage in a sagittal plane. The ribs will be counted until the 5th rib is identified in the midaxillary line. The latissimus dorsi, teres major and serratus muscles will be then easily identifiable by US overlying the fifth rib. The needle will be introduced in-plane with respect to the US probe from supero-anterior to postero-inferior
Also known as: Serratus anterior plane block( SAP) group
First pain medication request
Time to the first pain medication request till application of the block
Time frame: 24 hours
Time of pain onset
Time of onset of Pain
Time frame: 24 hours
Hemodynamics (heart rate)
Hemodynamics in the form of heart rate "beats per minute"
Time frame: 24 hours
Hemodynamics (ABP)
Hemodynamics in the form of arterial blood pressure" mm Hg".
Time frame: 24 hours
Nausea and vomiting
Postoperative nausea and vomiting
Time frame: 24 hours
Plan to share: No — Via scholar Gate
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This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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Cairo University