An observational study in Bullous Keratopathy, sponsored by Prince of Wales Hospital, Shatin, Hong Kong. Completed. Per ClinicalTrials.gov, last updated 2018-03-02.
Sponsored by Prince of Wales Hospital, Shatin, Hong Kong · Observational
A retrospective study including 22 patients who have undergone amniotic membrane transplant in our unit up till 2016. Confocal microscopy and anterior segment optical coherence tomography (ASOCT) were performed to assess the retention of amniotic membrane and to detect any corneal structural changes. Comparison was made with 5 controls who had bullous keratopathy awaiting endothelial keratoplasty.
This retrospective cohort study (CREC Ref No.: CRE-2013.687) was approved by the Joint Chinese University of Hong Kong-New Territories East Cluster Clinical Research Ethics Committee. All patients who had AMT done due to symptomatic bullous keratopathy at the Prince of Wales Hospital and Alice Ho Miu Ling Nethersole Hospital (from 1998 onwards till June 2016) were invited back for confocal microscopy and anterior segment optical coherence tomography (ASOCT) at the clinic by the principal investigator (GS) from October to November 2016.
Cases who have undergone amniotic membrane transplant in our unit up till 2016 and controls who had bullous keratopathy awaiting endothelial keratoplasty
Exclusion Criteria:
patients who have undergone amniotic membrane transplant in our unit up till 2016.
Procedure: Amniotic membrane transplant
bullous keratopathy patients awaiting endothelial keratoplasty
Amniotic membrane graft was transplanted onto the bullous cornea by the inlay technique
Amniotic membrane retention
Amniotic membrane retention in the cornea was assessed with confocal microscopy
Time frame: from date of operation till 2016
Pain
pain score (from 0-10, scale interval 1, 0 no pain, 10 most painful)reduction after amniotic membrane tranplant
Time frame: from date of operation till 2016
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.
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Prince of Wales Hospital, Shatin, Hong Kong