An observational study in Neurogenic Bladder and Overactive Detrusor, sponsored by Swiss Paraplegic Research, Nottwil. Completed at 1 site in Switzerland. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2019-08-06.
Sponsored by Swiss Paraplegic Research, Nottwil · Observational
Among 15 studies in Urinary Bladder, Neurogenic with a site in Switzerland — 2 open to participants now, 2 under way, 1 of them phase 3. Urinary Bladder, Neurogenic · Switzerland.
Among the 15 studies in Urinary Bladder, Neurogenic with a site in Switzerland, this one is the only one that started in 2018, is one of 7 observational ones, and was the 11th registered.
189 studies on the registry are indexed under Urinary Bladder, Neurogenic; 40 are open to participants now.
Browse Urinary Bladder, Neurogenic studies →2 of the 15 studies in Urinary Bladder, Neurogenic with a site in Switzerland are open now. Recruiting first, the newest first:
Centre Hospitalier Universitaire Vaudois · Sites in Switzerland
University of Zurich · Sites in Switzerland
A study can be open while its sites in Switzerland have not opened yet or have stopped. Only those recruiting at a site in Switzerland →
Of the 26 Urinary Bladder, Neurogenic studies recruiting now, 12 (46%) set no upper age limit and 9 (35%) stop at 75 or younger; 7 take children under 18; 1 take healthy volunteers.
This study: 18 Years to 99 Years · all sexes · no healthy volunteers.
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15 studies; the count open now beside each. This study's row is marked.
First in 2007; this study’s year is marked. 1 started in 2018.
This study's enrollment of 56 is below the median of 71 across 57 observational studies indexed under Urinary Bladder, Neurogenic.
Median enrollment 44 across the 8 interventional studies, 55 across the 7 observational. Of the 13 that completed or were terminated, 1 (8%) have results posted.
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2 of 15 have an industry lead sponsor. The 7 most frequent:
Swiss Paraplegic Research, Nottwil is the lead sponsor of 71 studies on the registry; 8 are open to participants now.
Swiss Paraplegic Research, Nottwil has 4 studies filed under Urinary Bladder, Neurogenic — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 15 studies in Urinary Bladder, Neurogenic with a site in Switzerland, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The changes in bladder function after the injection of Onabotulinum toxin into the detrusor in individuals with neurogenic bladder overactivity will be investigated retrospectively. The records of all patients treated with Onabotulinum toxin injections into the detrusor since 2000 will be evaluated. The changes in the urodynamic values after the injection of 300 units of Onabotulinum toxin will be compared with the changes after the injection of 200 units. Furthermore, the differences in urinary continence, duration between injections, side effects and complications between the two groups will be investigated.
patients treated with Onabotulinum toxin for neurogenic detrusor overactivity as a result of spinal cord injury
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Drug: Injection of Onabotulinum toxin
Drug: Injection of Onabotulinum toxin
multiple injections of Onabotulinum toxin into the detrusor muscle
change in detrusor pressure post-injection
bladder detrusor pressure during storage phase
Time frame: within 3 months before injection; within 2 months after injection
maximum bladder volume
Time frame: within 3 months before injection; within 2 months after injection
bladder compliance
The relationship between a change in bladder volume and the change in detrusor pressure (ΔDV/ΔDP).
Time frame: within 3 months before injection; within 2 months after injection
reflexive bladder volume
Time frame: within 3 months before injection; within 2 months after injection
complications
Time frame: within 2 months after injection
presence of urinary incontinence
Time frame: within 3 months before injection; within 2 months after injection
lesion level
Time frame: at the time of spinal cord injury
lesion severity
Time frame: at the time of spinal cord injury
method of bladder evacuation
evacuation by intermittent catheterization, reflex voiding, suprapubic catheter , electric stimulation
Time frame: within 2 months after injection
Ran from Feb 2018 to primary completion in Apr 2019, 14 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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Swiss Paraplegic Research, Nottwil