An interventional study of adapted STMST in Emotional Stress, sponsored by NIZO Food Research. Completed at 1 site in Netherlands. Open to male participants aged 18 Years to 34 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-09-05.
Sponsored by NIZO Food Research · Not applicable, Interventional, and Basic science
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Among 13 studies in Stress, Psychological with a site in Netherlands — 2 open to participants now, 3 under way, none of them phase 3. Stress, Psychological · Netherlands.
Among the 13 studies in Stress, Psychological with a site in Netherlands, this one is the 9th largest by enrollment of the 11 interventional ones that give a count, is the only one that started in 2017, is one of 10 with no phase, and was the 2nd registered.
848 studies on the registry are indexed under Stress, Psychological; 139 are open to participants now.
Browse Stress, Psychological studies →2 of the 13 studies in Stress, Psychological with a site in Netherlands are open now. Recruiting first, the newest first:
GGZ Centraal · Sites in Netherlands
Ages 18+
Comprehensive Cancer Centre The Netherlands · Sites in Netherlands
Ages 18+
A study can be open while its sites in Netherlands have not opened yet or have stopped. Only those recruiting at a site in Netherlands →
Of the 75 Stress, Psychological studies recruiting now, 34 (45%) set no upper age limit and 37 (49%) stop at 75 or younger; 14 take children under 18; 49 take healthy volunteers.
This study: 18 Years to 34 Years · male · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
13 studies; the count open now beside each. This study's row is marked.
First in 2007; this study’s year is marked. 1 started in 2017.
This study's enrollment of 30 is below the median of 84 across 692 interventional studies indexed under Stress, Psychological.
Median enrollment 55 across the 11 interventional studies, 541 across the 2 observational. Of the 8 that completed or were terminated, 0 (0%) have results posted.
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2 of 13 have an industry lead sponsor. The 10 most frequent:
NIZO Food Research is the lead sponsor of 19 studies on the registry; none are open to participants now.
NIZO Food Research has 1 study filed under Stress, Psychological — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 13 studies in Stress, Psychological with a site in Netherlands, from their registry updates:
Nothing recorded among them since 2026-09-25.
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In the MOIST study it will be assessed whether the adapted Sternberg short-term working memory task (STMST) is an effective method to induce malodor formation by emotional stress, as assessed by expert assessments of stress-induced malodor formation in the armpits of 30 healthy male volunteers.
Before, during and after being exposed to the adapted version of the STMST, saliva will be collected to determine cortisol levels, subjects have to rate their momentary feelings of anxiety and embarrassment and heart rate variability will be monitored continuously with a wireless signal transmission device. Before and after exposure to the adapted STMST, malodor levels will be assessed by two expert judges, axillary volatiles will be collected by cup scrubbing and microbiota samples will be taken to determine microbial species.
Stress is a primary physiological response to physical and/or social threats resulting from a complex interplay of neurophysiological and psychological factors. Cognitive interpretations of social-evaluative threats have been found to be very potent emotional stressors. Apocrine sweat glands are stimulated by emotional stress, fear or mental tension. Upon secretion, apocrine sweat is odorless. By enzymatic action of the bacterial microbiome on apocrine sweat in particular, body malodor is formed. This is perceived as offensive by most societies. As a result, self-confidence and social relationships can be influenced by undesired body odor. A good understanding of the complex sweat-microbiome interactions leading to malodor formation is required for the development of effective malodor remedies.
In the MOIST study it will be assessed whether the adapted Sternberg short-term working memory task (STMST) is an effective method to induce malodor formation by emotional stress, as assessed by expert assessments of stress-induced malodor formation in the armpits of 30 healthy male volunteers.
Before, during and after being exposed to the adapted version of the STMST, saliva will be collected to determine cortisol levels, subjects have to rate their momentary feelings of anxiety and embarrassment and heart rate variability will be monitored continuously with a wireless signal transmission device. Before and after exposure to the adapted STMST, malodor levels will be assessed by two expert judges, axillary volatiles will be collected by cup scrubbing and microbiota samples will be taken to determine microbial species.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants are subjected to the adapted STMST to induce emotional sweating.
Other: adapted STMST
Participants are subjected to the adapted STMST to induce emotional sweating.
stress-induced malodor formation
Expert assessments of stress-induced malodor formation by emotional stress in the armpits of healthy male volunteers
Time frame: Change from baseline malodour formation 20 min, 40 min, and 60 minutes after the start of exposure to the adapted STMST
Salivary cortisol
Emotional stress in healthy male volunteers as assessed by cortisol in saliva
Time frame: Change from baseline salivary cortisol 5 min, 20 min, 30 min, 40 min, 50 min, 60 min, and 70 minutes after the start of exposure to the adapted STMST
Self-assessed mood state
Emotional stress in healthy male volunteers as assessed by self-assessed mood state (VAS)
Time frame: Change from baseline self-assessed mood state 5 min, 20 min, 30 min, 40 min, 50 min, 60 min, 70 min, and 90 minutes after the start of exposure to the adapted STMST
Malodor compounds formation
The malodor compounds formation as assessed by GC-MS/MS analyses during conditions of emotional sweating
Time frame: Change from baseline malodour compounds formation 75 minutes after the start of exposure to the adapted STMST
Plan to share: No
No publications or documents are linked to this record.
Ran from Oct 2017 to primary completion in Nov 2017, 0 months.
Of 459 non-industry interventional studies with no phase under Stress, Psychological, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 26. This study's 0 months is below that.
Counting every sponsor, half of 472 studies reached it within 13 months; a quarter within 5 and three quarters within 26.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.
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NIZO Food Research