An observational study in Microbiota, Pneumonia, Bacterial and Respiratory Failure, sponsored by Taichung Veterans General Hospital. Completed at 1 site in Taiwan. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2019-09-16.
Sponsored by Taichung Veterans General Hospital · Observational
Among 12 studies in Pneumonia, Bacterial with a site in Taiwan — 2 open to participants now, 2 under way, 1 of them phase 3. Pneumonia, Bacterial · Taiwan.
Among the 12 studies in Pneumonia, Bacterial with a site in Taiwan, this one is the only one that started in 2017, is one of 3 observational ones, and was the 6th registered.
153 studies on the registry are indexed under Pneumonia, Bacterial; 27 are open to participants now.
Browse Pneumonia, Bacterial studies →2 of the 12 studies in Pneumonia, Bacterial with a site in Taiwan are open now. Recruiting first, the newest first:
TTY Biopharm · Sites in Taiwan
Ages 18+
Taipei Medical University WanFang Hospital · Sites in Taiwan
Ages 18+
A study can be open while its sites in Taiwan have not opened yet or have stopped. Only those recruiting at a site in Taiwan →
Of the 18 Pneumonia, Bacterial studies recruiting now, 12 (67%) set no upper age limit and 2 (11%) stop at 75 or younger; 2 take children under 18; 1 takes healthy volunteers.
This study: 40 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
12 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 2 3 · Phase 3 5
First in 2007; this study’s year is marked. 1 started in 2017.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 200 is below the median of 224 across 39 observational studies indexed under Pneumonia, Bacterial.
Median enrollment 126 across the 9 interventional studies, 200 across the 3 observational. Of the 9 that completed or were terminated, 5 (56%) have results posted.
This tab as a report to print or save as PDF → With an account.
7 of 12 have an industry lead sponsor. The 10 most frequent:
Taichung Veterans General Hospital is the lead sponsor of 175 studies on the registry; 39 are open to participants now.
Taichung Veterans General Hospital has 1 study filed under Pneumonia, Bacterial — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 12 studies in Pneumonia, Bacterial with a site in Taiwan, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
A prospective observational study. Enrolled participants admitted to ICU due to pneumonia and respiratory failure need mechanical ventilator support. Investigators collected the residual specimens, such as sputum from endotrachea aspiration, bronchoalveolar lavage fluid in those participants as the usual care in the ICU. Those residual samples were sent to extract RNA and sequence by using high-throughput sequencing (next-generation sequencing) method.
Investigators will compared the microbiome feature between lower respiratory tract and stool specimens in those participants diagnosed as pneumonia with respiratory failure.
Patients who suffered from pneumonia and respiratory failure needed mechanical ventilator support with inform consent will be enrolled into study
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Sputum and stool sampling day 1, 3 and 7 after enrolling into study
Diagnostic Test: 16s RNA sequence of sputum, bronchoalveolar lavage fluid (options), stool
We will check the microbiome in lower respiratory samples (sputum and bronchoalveolar lavage fluid) and stool by using 16S RNA sequencing
The dynamics of the airway bacterial microbiome in the lower respiratory tract specimens in the setting of pneumonia accompanied by respiratory failure at the onset of, and day 3 and day 7 (or before extubation)
Uses high-throughput sequencing (next-generation sequencing) to sequence the 16S rRNA sequence of bacteria in residual samples
Time frame: Compared the dynamic change of mirobiome at the baseline (onset of respiratory failure within 48 hours)m day 3 and day 7
The dynamics of the gut bacterial microbiome in the stool specimens in the setting of pneumonia accompanied by respiratory failure at the onset of, and day 3 and day 7 (or before extubation)
uses high-throughput sequencing (next-generation sequencing) to sequence the 16S
Time frame: Compared the dynamic change of mirobiome at the baseline (onset of respiratory failure within 48 hours)m day 3 and day 7
The association of the microbiome between lower respiratory tracts and stool specimens in pneumonic patient with respiratory failure
Uses high-throughput sequencing (next-generation sequencing) to sequence the 16S
Time frame: Compared the association of mirobiome at the baseline (onset of respiratory failure within 48 hours)m day 3 and day 7
Plan to share: Yes — We will share study protocol and Informed Consent Form and Clinical Study Report to other researchers
Supporting information: Study protocol, Informed consent form, Clinical study report
Time frame: One year after the study was completed
Access criteria: E-mail to yetquen@gmail.com Dr. Pin-Kuei Fu
No publications or documents are linked to this record.
Ran from Aug 2017 to primary completion in Sep 2019, 24 months.
Of 22 observational studies under Pneumonia, Bacterial, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 49. This study's 24 months is close to that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Taichung Veterans General Hospital →