An interventional study of High-Carbohydrate Sedentary and High-Carbohydrate Active in Physical Activity and Diet Modification, sponsored by University of British Columbia. Completed at 1 site in Canada. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-25.
Sponsored by University of British Columbia · Not applicable, Interventional, and Other
Among 96 studies in Motor Activity by University of British Columbia — 24 open to participants now, 26 under way, none of them phase 3. Motor Activity · University of British Columbia.
Among the 96 studies in Motor Activity by University of British Columbia, this one is the 67th largest by enrollment of the 92 interventional ones that give a count, is one of 5 that started in 2017, is one of 88 with no phase, and was the 44th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →24 of the 96 studies in Motor Activity by University of British Columbia are open now, in 1 country. Recruiting first, the newest first:
University of British Columbia · Sites in Canada
University of British Columbia · Sites in Canada
University of British Columbia · Sites in Canada
University of British Columbia · Sites in Canada
University of British Columbia · Sites in Canada
By country, each count listing its studies:
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
96 studies; the count open now beside each. This study's row is marked.
First in 2005; this study’s year is marked. 5 started in 2017.
This study's enrollment of 23 is below the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Median enrollment 61 across the 92 interventional studies, 35 across the 4 observational. Of the 58 that completed or were terminated, 12 (21%) have results posted.
This tab as a report to print or save as PDF → With an account.
University of British Columbia is the lead sponsor of 1,339 studies on the registry; 259 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 1 (17%) have results posted.
11 of the studies in Motor Activity by University of British Columbia that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07717710University of British ColumbiaIvabradine for Heart Rate Reduction During Exercise in Healthy Adults | 2026-12 |
| NCT06195423University of British ColumbiaStopping OsteoARthritis After an ACL Tear | 2026-12-30 |
| NCT07443293University of British ColumbiaIMPACT 360 for Parkinson's Disease | 2026-12-31 |
| NCT04299945University of British ColumbiaEffects of Drinking Beetroot Juice on Exercise Performance in Patients With Fibrotic Interstitial Lung Disease | 2026-12-31 |
| NCT07212712University of British ColumbiaThe Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans | 2026-12-31 |
Among the 96 studies in Motor Activity by University of British Columbia, from their registry updates:
This tab as a report to print or save as PDF → With an account.
Prolonged sitting has been shown to impair metabolism and vascular function. The overall purpose of this study is to determine if breaking up prolonged (9 hours) of sitting with brief (\~20 second) stair climbing exercise "snacks" can improve markers of metabolic control and vascular health in healthy young male participants and in males or females with overweight/obesity who are at risk of insulin resistance. An additional purpose is to determine if saliva insulin can be used as a valid indicator of blood insulin when measured throughout the day in sedentary and active conditions and when diets with different amounts of carbohydrates are consumed.
Lean Group Inclusion Criteria:
Non-smoking
Lean Group Exclusion Criteria:
Diagnosed with diabetes or prediabetes (fasting blood sugar more than 6.0 mmol/l) or any other chronic condition that may impact glucose or insulin levels.
is over 25 kg/m2 Take medications which may affect glucose and insulin levels Allergic to eggs. Smoker Competitive or serious endurance athlete.
Overweight/Obese Group Inclusion Criteria:
Elevated waist circumference (>102 cm for male and >88 cm for female)
Overweight/Obese Group Exclusion Criteria:
Diagnosed with diabetes (fasting blood sugar more than 7.0 mmol/l) Take medications which may affect glucose and insulin levels Allergic to eggs. Smoker Competitive or serious endurance athlete.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will remain seated for 9 hours (except for using the restroom) while consuming a high-carbohydrate diet (3 meals)
Behavioral: High-Carbohydrate Sedentary
Participants will remain seated for 9 hours (except for using the restroom) while consuming a high-carbohydrate diet (3 meals) but will complete 8 stair climbing sprint "snacks" once per hour involving ascending 3 flights of stairs at a vigorous pace (\~20 seconds each).
Behavioral: High-Carbohydrate Active
Participants will remain seated for 9 hours (except for using the restroom) while consuming a low-carbohydrate diet (3 meals)
Behavioral: Low-carbohydrate Sedentary
Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period.
Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period except that once every hour they will ascend three flights of stairs vigorously (stair climbing sprint "snack") for a total of 8 active breaks.
Three low-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period. This condition will provide a condition where the blood glucose and insulin responses are relatively low and stable throughout the day.
Plasma insulin area under the curve
The plasma insulin concentration measured by enzyme-linked immunosorbent assay area under the curve will be measured using the trapezoidal rule.
Time frame: Measured across 9 hours of each intervention day
Saliva insulin area under the curve
The saliva insulin concentration measured by enzyme-linked immunosorbent assay area under the curve will be measured using the trapezoidal rule.
Time frame: Measured across 9 hours of each intervention day
Plasma glucose area under the curve
The plasma glucose concentration measured by hexokinase method area under the curve will be measured using the trapezoidal rule.
Time frame: Measured across 9 hours of each intervention day
Plasma triglyceride area under the curve
The plasma triglyceride concentration measured by biochemical assay area under the curve will be measured using the trapezoidal rule.
Time frame: Measured across 9 hours of each intervention day
Plasma non-esterified fatty acids area under the curve
The plasma non-esterified fatty acid concentration measured by biochemical assay area under the curve will be measured using the trapezoidal rule.
Time frame: Measured across 9 hours of each intervention day
Femoral artery flow-mediated dilation
Flow-mediated dilation of femoral artery measured by vascular ultrasound
Time frame: Measured in the morning (time 0 hours) and afternoon (time 8.5 hours) each intervention day
Cerebrovascular function
Cerebrovascular function measured by transcranial doppler ultrasound
Time frame: Measured in the morning (time 0.5 hours) and afternoon (time 6 hours) each intervention day
Cognitive function
Cognitive function measured by Computerized Neurocognitive Assessment Software (CNS) Vital Signs test battery
Time frame: Measured in the morning (time 0.5 hours) and afternoon (time 6 hours) each intervention day
Plan to share: Undecided — We will share individual patient data (de-identified) with researchers upon request.
Ran from Oct 2017 to primary completion in Jun 2019, 20 months.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 20 months is above that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
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University of British Columbia →