An observational study in Frail Elderly Syndrome, Surgery and Outcomes, sponsored by Ottawa Hospital Research Institute. Completed. Open to participants aged 66 Years and older. Per ClinicalTrials.gov, last updated 2024-09-23.
Sponsored by Ottawa Hospital Research Institute · Observational
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.
Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,
All individuals 66 years of older on the day of their surgery
Exclusion Criteria:
Individuals having major noncardiac surgery following an elective hospital admission
Diagnostic Test: Frailty index
Individuals having general surgery following an urgent hospital admission
Diagnostic Test: Frailty index
A frailty index composed of variables from health administrative data that cover multi-system health issues. Deficits will be coded as present or absent, and the number of deficits present will be divided by the total number of deficits present to provide an overall score between 0-1.
Survival for One Year After Surgery
Still being alive (no death date) in the registered persons database Outcome is binary, exposure is per 0.1 unit increase
Time frame: Date of surgery to 365 days after surgery
Institutional Discharge
Discharge to long term care or continuing care facility at the time of hospital discharge
Time frame: Date of surgery to date of hospital discharge, or up to one year after surgery (whichever comes first)
| Milestone | Elective | Emergency |
|---|---|---|
| Started | 415704 | 95581 |
| Completed | 415704 | 95581 |
| Not completed | 0 | 0 |
Still being alive (no death date) in the registered persons database Outcome is binary, exposure is per 0.1 unit increase
| Participants | Elective Surgery | Emergency Surgery |
|---|---|---|
| Survival for One Year After Surgery | 396164 | 0 |
Discharge to long term care or continuing care facility at the time of hospital discharge
| Participants | Elective Surgery | Emergency Surgery |
|---|---|---|
| Institutional Discharge | 57666 | 0 |
Collected over 1 year. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Elective Noncardiac Surgery | 19,540/415,704 (4.7%) | — | — |
| Emergency General Surgery | — | — | — |
| Age, Continuous(years) | Elective Surgery | Emergency Surgery | Total |
|---|---|---|---|
| Frail | 76 ± 6 | 76 ± 6 | 76 ± 6 |
| Not Frail | 73 ± 6 | 73 ± 6 | 73 ± 6 |
| Sex: Female, Male(Participants) | Elective Surgery | Emergency Surgery | Total |
|---|---|---|---|
| Frail — Female | 58953 | 21420 | 80373 |
| Frail — Male | 60871 | 18618 | 79489 |
| Not Frail — Female | 165693 | 30493 | 196186 |
| Not Frail — Male | 130187 | 25050 | 155237 |
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.
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Ottawa Hospital Research Institute