An interventional study of transsphenoidal surgery treatment and dopamine agonist treatment in Prolactinoma, sponsored by First Affiliated Hospital, Sun Yat-Sen University. Recruiting at 1 site in China. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2017-11-24.
Sponsored by First Affiliated Hospital, Sun Yat-Sen University · Not applicable, Interventional, and Treatment
the study aim to investigate the endocrine remission rate of non-invasive prolactinoma between transsphenoidal surgery treatment and Dopamine agonist treatment.
Non-invasive prolactinomas were treated by transsphenoidal surgery or Dopamine agonist until now. However，this two type therapies were controversial. The study aim to investigate the endocrine remission rate of non-invasive prolactinoma between transsphenoidal surgery treatment and Dopamine agonist treatment.
28 studies on the registry are indexed under Prolactinoma; 5 are open to participants now.
This study's planned enrollment of 394 is above the median of 55 across 14 interventional studies indexed under Prolactinoma.
Browse Prolactinoma studies →First Affiliated Hospital, Sun Yat-Sen University is the lead sponsor of 162 studies on the registry; 54 are open to participants now.
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non-invasive prolactionma
Exclusion Criteria:
invasive prolactioma
Transsphenoidal surgery treat non-invasive prolactinoma by experienced neurosurgeon
Procedure: transsphenoidal surgery treatment
Minimum effective dose of dopamine agonist, bromocriptine, treat non-invasive prolactinoma
Drug: dopamine agonist treatment
transsphenoidal surgery treatment
Also known as: TSS
Minimum effective dose of dopamine agonist，bromocriptine，treat prolactinona
Also known as: DA
Endocrine remission rate
After intervention, blood prolactin normalization rate
Time frame: five-year
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