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CompletedNCT03347825PORTaLUpdated Feb 3, 2021

Retrospective Multi-Center Study to Compare Perioperative Outcomes for Robotic-assisted Lobectomy With Those Associated With VATS and Open Lobectomy for Lung Cancer

An observational study in Lung Cancer, sponsored by Intuitive Surgical. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-02-03.

Sponsored by Intuitive Surgical · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
7,000
Ages
18 Years and older
Sex
All
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Study summary

The main objective of this study is to evaluate and compare peri-operative outcomes of lobectomy compare with different approaches. The study aims to include patients with stage IA, IB, IIA, IIB and IIIA lung cancer that underwent lobectomy via robotic-assisted, VATS and open approach.

Read the detailed description

This is a multi-center, retrospective chart review study of all consecutive lobectomies performed for clinical stage IA, IB, IIA, IIB and IIIA lung cancer, performed by participating surgeons at their respective institutions that meet all inclusion and exclusion criteria. All cases of lobectomy performed for clinical stages, IA, IB, IIA, IIB and IIIA lung cancer via robotic-assisted, VATS (video assisted thoracic surgery) and open approach that meet the study inclusion and exclusion criteria will be considered for inclusion in the study. The chart review and data collection will be performed in a reverse chronological order starting at 30 days prior to IRB approval of the study at the institution and going back to 2013 (i.e most current data in 2017 and chronologically going back through 2013). The retrospective chart review and data collection is anticipated to occur in two phases:

Baseline patient characteristics, perioperative and post-operative short term clinical and pathological outcomes data will be obtained from hospital records. Each participating institution will contribute approximately 100-800 cases from one or more surgeons. Since the data will have been de-identified, and is archival in nature, there will be no active subject recruitment and no patient consenting is required

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Conditions studied

  • Lung Cancer

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03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Patients who underwent robotic-assisted, VATS or open lobectomy for primary stage IA, IB, IIA, IIB and IIIA lung cancer, with or without neo-adjuvant therapy.

Inclusion criteria

  • Subject is 18 years or older
  • Subject who has undergone elective robotic-assisted, VATS or open lobectomy for clinically diagnosed primary stage IA, IB, IIA, IIB and IIIA lung cancer, with or without neo-adjuvant therapy

Exclusion criteria

Exclusion Criteria:

  • Subject with stage IIIB lung cancer
  • Subject who received lobectomy as an emergent procedure
  • Subjects who received lobectomy for metastatic cancer
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
7,000 participants (actual)
Patient registry
No

Groups and cohorts

  • Robotic-assisted lobectomy

    Pre-operative, intra-operative and post-operative clinical, surgical and oncological information will be obtained from institutional records for patients who underwent robotic-assisted lobectomy for lung cancer.

    Procedure: Robotic-assisted lobectomy using da Vinci Surgical System

  • VATS (video assisted thoracic surgery) lobectomy

    Pre-operative, intra-operative and post-operative clinical, surgical and oncological information will be obtained from institutional records for patients who underwent VATS lobectomy for lung cancer.

    Procedure: VATS (video assisted thoracic surgery)

  • Open lobectomy

    Pre-operative, intra-operative and post-operative clinical, surgical and oncological information will be obtained from institutional records for patients who underwent open lobectomy for lung cancer.

    Procedure: Open lobectomy

Interventions

  • ProcedureRobotic-assisted lobectomy using da Vinci Surgical System

    Robotic-assisted lobectomy

  • ProcedureVATS (video assisted thoracic surgery)

    VATS (video assisted thoracic surgery)

  • ProcedureOpen lobectomy

    Open lobectomy

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What researchers measure

Primary outcomes

  1. Chart review and data collection of clinical stage IB, IIA, IIB, IIIA cases

    Compare peri-operative outcomes of robotic-assisted lobectomy with those associated with VATS and open lobectomy for lung cancer

    Time frame: 2013-2019

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Study locations

1 site
  • BaylorScott&White
    Dallas, Texas 75093, United States
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Registry details

Key details

Study ID
NCT03347825
Lead sponsor
Intuitive Surgical
Responsible party
Sponsor
First posted
Nov 20, 2017
Start date
Feb 1, 2018
Primary completion
Jul 1, 2020
Completion
Jul 1, 2020
Last update
Feb 3, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.

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