An interventional study of Pulsed Electromagnetic Field therapy (PEMF) and Pulsed Electromagnetic Field Sham therapy in Healthy, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-04-11.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Basic science
Among 42 studies in Motor Activity by Mayo Clinic — 4 open to participants now, 5 under way, none of them phase 3. Motor Activity · Mayo Clinic.
Among the 42 studies in Motor Activity by Mayo Clinic, this one is the 11th largest by enrollment of the 36 interventional ones that give a count, is one of 6 that started in 2016, is one of 28 with no phase, and was the 25th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →4 of the 42 studies in Motor Activity by Mayo Clinic are open now, in 1 country. Recruiting first, the newest first:
Mayo Clinic · Sites in United States
Mayo Clinic · Sites in United States
Mayo Clinic · Sites in United States
Mayo Clinic · Sites in United States
By country, each count listing its studies:
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
42 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 5 · Phase 2 3 · Phase 3 2
First in 2003; this study’s year is marked. 6 started in 2016.
This study's enrollment of 72 is above the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Median enrollment 53 across the 36 interventional studies, 34 across the 6 observational. Of the 35 that completed or were terminated, 7 (20%) have results posted.
This tab as a report to print or save as PDF → With an account.
Mayo Clinic is the lead sponsor of 3,269 studies on the registry; 672 are open to participants now.
Of its 452 completed or terminated interventional studies of FDA-regulated products, 321 (71%) have results posted.
3 of the studies in Motor Activity by Mayo Clinic that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06880861Mayo ClinicInvestigating Memory and Physical Activity After Cancer Treatment in Survivors of Adolescent and Young Adult Cancers | 2026-12-15 |
| NCT06730906Mayo ClinicPACTAID App in Adults With Type 1 Diabetes to Help Manage Exercise | 2026-12-28 |
| NCT04816006Mayo ClinicBreast Cancer, Reasoning, and Activity Intervention | 2027-07-31 |
Among the 42 studies in Motor Activity by Mayo Clinic, from their registry updates:
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This research is being done to better understand the pulmonary consequences of completing an ultra marathon at altitude and a sea level city.
Subjects will be asked to undertake three (3) sets of assessments at prescribed time intervals: Baseline (at 72-24h prior to each event), immediately post (within 2h of race completion) and during recovery (within 24-48h of race completion). Each assessment will consist of 1)lung function tests; 2) a saliva and blood sample; 3) a lung and cardiac ultrasound. Subjects will be recruited from a range of age groups and fitness levels, before being divided into a sham or therapy group. Groups will use Pulsed Electromagnetic Field (PEMF) therapy or related sham before the event and during recovery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Healthy endurance trained individuals participating in the Ultra Trail du Mont Blanc (UTMB) and/or Hong Kong 100 ultramarathons
Exclusion Criteria:
> 65 years age
20 athletes (ideally a mix of elite and amateur level athletes and veteran (40-65y) and young (20-39y). Athletes will be recruited at the 2018 and 2019 Hong Kong 100 races. In addition, these athletes will use the pulsed electromagnetic field (PEMF) for the two weeks prior to the race.
Procedure: Pulsed Electromagnetic Field therapy (PEMF)
20 athletes (ideally a mix of elite and amateur level athletes and veteran (40-65y) and young (20-39y). Athletes will be recruited at the 2018 and 2019 Hong Kong 100 races. In addition, these athletes will use a PEMF device that doesn't produce electromagnetic fields (sham) for the two weeks prior to the race.
Procedure: Pulsed Electromagnetic Field Sham therapy
20 athletes (ideally a mix of elite and amateur level athletes and veteran (40-65y) and young (20-39y). Athletes will be recruited at the 2018 and 2019 Ultra Trail du Mont Blanc (UTMB) races. In addition, these athletes will use the pulsed electromagnetic field (PEMF) for the two weeks prior to the race.
Procedure: Pulsed Electromagnetic Field therapy (PEMF)
20 athletes (ideally a mix of elite and amateur level athletes and veteran (40-65y) and young (20-39y). Athletes will be recruited at the 2018 and 2019 Ultra Trail du Mont Blanc (UTMB) races. In addition, these athletes will use a PEMF device that doesn't produce electromagnetic fields (sham) for the two weeks prior to the race.
Procedure: Pulsed Electromagnetic Field Sham therapy
PEMF Therapy based on Biological Electromagnetic (BEM) microbial wave technology provides micro-magnetic emissions to the center of the palm (Laogong acupoint). While participating in the study, the subjects will undertake 2 sessions of therapy every day (1 session in the morning and evening). Each session will last for 16-min (8-min for left and 8-min for right hand).
Also known as: Bioboosti
PEMF therapy will be administered however it will not produce micro-magnetic emissions. The therapy will be used on the center of the palm (Laogong acupoint) of each hand. While participating in the study, the subjects will undertake 2 sessions of therapy every day (1 session in the morning and evening). Each session will last for 16-min (8-min for left and 8-min for right hand).
Also known as: Bioboosti Sham
Change in right ventricle end diastolic area (EDA)
Cardiac ultrasound (Philips CX50) will be performed to determine left and right ventricular morphology and function. Ultrasound will be performed in accordance with the recommendations of the American Society of Echocardiography guidelines (ASE). Imaging of the ventricles and the diameter during relaxation (diastole) will be captured and evaluated. Normal value for right ventricle EDA indexed to body surface area ranges between 5-12.6 cm\^2/m\^2 for males and 4.5-11.5 cm\^2/m\^2 for females .
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in tricuspid annular plane systolic excursion (TAPSE)
Another ultrasound metric that will be evaluated is tricuspid annular plane systolic excursion (TAPSE) which is used a parameter of global RV function which describes apex-to-base shortening. Normal value for TAPSE is above 16 mm.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in ratio between early mitral inflow velocity and mitral annular early diastolic velocity (E/e')
Another ultrasound metric that will be evaluated is early mitral inflow velocity and mitral annular early diastolic velocity (E/e') which is used to evaluate the diastolic or relaxation function of the left ventricle. Normal value for E/e' is \<6.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in the ratio of peak velocity flow in early diastole (the E wave) to peak velocity flow in late diastole caused by atrial contraction (the A wave)
Another ultrasound metric that will be evaluated is he ratio of peak velocity flow in early diastole (the E wave) to peak velocity flow in late diastole caused by atrial contraction (the A wave) (E/A) which is used to evaluate the diastolic filling of the left ventricle. Normal value for E/A is between 0.8 and 2.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in lung fluid assessed through ultrasound incidence of comet tails
Ultrasound will be used to image 28 "windows" covering the 2nd through the 5th intercostal/rib space on the right and left sides of the chest. The number of comet tails observed over these 28 locations will be documented and the change in this number over the course of the study will be evaluated.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in lung fluid assessed through diffusion capacity of the lungs for carbon monoxide and nitric oxide
Subjects will take a maximal breath of a test gas mixture, hold that inhalation for 4 seconds and then exhale and the exhaled gas will be analyze to determine the change in gas concentrations between what was inhaled and exhaled. Comparison will be made between the change over time in this ability of gas to move from the lungs to the blood stream.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in exhaled nitric oxide
The amount of nitric oxide in ones exhaled air will be measured by a handheld device. Levels under 25 parts per billion are normal, more than 35 parts per billion would be a sign of airway inflammation.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in hemoglobin
A blood sample will be taken and analyzed to determine the amount of red blood cells and and hemoglobin in the blood. For males normal range for hemoglobin is 13.5-17.5 grams per deciliter and for females normal range for hemoglobin is 12.0-15.5 grams per deciliter. Low values means anemia is present and higher levels is a normal response to altitude.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in hematocrit
A blood sample will be taken and analyzed to determine the amount of red blood cells and and hemoglobin in the blood. For males normal range for hematocrit is 38.8-50% and for females normal range for hematocrit is 34.9-44.5% Low values means anemia is present and higher levels is a normal response to altitude.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in cardiac troponin I
To determine if signs of cardiac damage, as its presence in the blood is a potential sign of damage to the heart muscle
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in B-type natriuretic peptide
To determine if signs of cardiac damage, as its presence in the blood is a potential sign of damage to the heart muscle
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Change in cortisol
Saliva levels of cortisol will be measured as a metric of stress. Cortisol levels increase when you body is under stress.
Time frame: baseline, within 2 hours of race completion, 24-48 hours post race
Ran from Dec 2016 to primary completion in Jun 2021, 54 months.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 54 months is above that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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