CClinicalTrials.gg
CompletedNCT03323086HIVUpdated Jan 7, 2020Results posted

Women SHARE Study: Reducing Sexual Risk

An interventional study of Brief Intervention (BI) with Technology Extender and Brochure in Alcohol and Substance-Related Mental Disorders and Sexually Transmitted Diseases, sponsored by The Miriam Hospital. Completed at 1 site in United States. Open to female participants aged 18 Years to 29 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-01-07.

Sponsored by The Miriam Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years to 29 Years
Sex
Female
01

Study summary

This study will investigate whether BI and technology extenders are feasible and acceptable for female patients at a reproductive health center (ages 18-29).

Read the detailed description

This study will assess the feasibility and acceptability, and obtain initial evidence of the efficacy, of the BI and technology extenders. At-risk women drinkers (N = 50) recruited from a reproductive health care clinic will be assessed, randomly assigned to the integrated BI or control (a Centers for Disease Control and Prevention-produced brochure with information about alcohol and women's health), and reassessed at 3 months to determine impact on alcohol use, condom use, and number of partners as well as hypothesized mediators.

02

Conditions studied

  • Alcohol and Substance-Related Mental Disorders
  • Sexually Transmitted Diseases
03

Who can participate

Ages eligible
18 Years to 29 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Female
  • Age 18-29 years
  • Meeting NIAAA definition of "at-risk" drinking (>3 drinks on any day in the last 3 months18 and/or >7 drinks per week)
  • Sexual risk behavior (i.e., last 3 months: vaginal/anal intercourse with >1 partner; vaginal/anal intercourse with a partner who has other partners; inconsistent condom use; new relationship (under 3 months))
  • English speaking
  • Absence of acute intoxication, depression, or suicidal ideation
  • No plans for relocation

Exclusion criteria

Exclusion Criteria:

  • Male
  • Under 18 years old or older than 29 years old
  • Non-English speaking
  • Suicidal Ideation
  • Relocating
  • Clinic provider advising against recruitment in the study
  • Unwilling or unable to provide consent
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
50 participants (actual)

Study arms

  • Experimental
    Brief Intervention (BI) with Technology Extender

    Participants assigned to BI condition will receive a face to face session lasting 45-60 minutes delivered by a health coach. Following the session, participants will be given access to a study website and receive texts-of-the day on study topics.

    Behavioral: Brief Intervention (BI) with Technology Extender

  • Other
    Brochure

    Participants assigned to the Brochure condition will receive materials prepared by the Centers for Disease Control and Prevention on the study topics.

    Other: Brochure

Interventions

  • BehavioralBrief Intervention (BI) with Technology Extender

    One, 45-60 minute BI, followed by three months of access to technology extenders

  • OtherBrochure

    Brochures provided one time

05

What researchers measure

Primary outcomes

  1. Feasibility of Providing Intervention

    percentage of individuals who attended their intervention

    Time frame: Immediately following intervention session (post-intervention), up to 30 minutes

Secondary outcomes

  1. Session Evaluation Questionnaire

    Measure Name: Session Evaluation Questionnaire; Construct Assessed: Treatment Satisfaction; Minimum total scale score = 1; Maximum total scale score = 5; Scoring: averaged ratings across 4 items; Interpretation: Higher scores represent a better outcome.

    Time frame: Immediately following intervention session (post-intervention), up to 30 minutes

  2. Number of Sexual Partners

    The number of male partners that the participant reported having penetrative sex with.

    Time frame: 3-month Follow-up

  3. Condomless Sex

    The number of occasions of condomless sex

    Time frame: 3-month Follow-up

  4. Alcohol Use Quantity

    The average number of drinks in a week

    Time frame: 3-month Follow-up

  5. Alcohol Use Binge Frequency

    The number of drinking occasions (single day) when 4 or more drinks are consumed

    Time frame: 3-month Follow-up

06

Results

Posted Jan 2, 2020

Participant flow

Participant flow — Overall Study
MilestoneBrief Intervention (BI) With Technology ExtenderBrochure
Started2622
Completed2320
Not completed32
Withdrew: Lost to follow-up32

Outcome measures

PrimaryFeasibility of Providing Intervention

percentage of individuals who attended their intervention

Time frame:
Immediately following intervention session (post-intervention), up to 30 minutes
Reported as:
Count of participants · Participants
Feasibility of Providing Intervention
ParticipantsBrief Intervention (BI) With Technology ExtenderBrochure
Feasibility of Providing Intervention2522
SecondarySession Evaluation Questionnaire

Measure Name: Session Evaluation Questionnaire; Construct Assessed: Treatment Satisfaction; Minimum total scale score = 1; Maximum total scale score = 5; Scoring: averaged ratings across 4 items; Interpretation: Higher scores represent a better outcome.

Time frame:
Immediately following intervention session (post-intervention), up to 30 minutes
Reported as:
Mean · units on a scale
Session Evaluation Questionnaire
units on a scaleBrief Intervention (BI) With Technology ExtenderBrochure
Session Evaluation Questionnaire4.65 ± 0.363.98 ± 0.96
SecondaryNumber of Sexual Partners

The number of male partners that the participant reported having penetrative sex with.

Time frame:
3-month Follow-up
Reported as:
Mean · partners
Number of Sexual Partners
partnersBrief Intervention (BI) With Technology ExtenderBrochure
Number of Sexual Partners3.23 ± 3.224.00 ± 3.08
SecondaryCondomless Sex

The number of occasions of condomless sex

Time frame:
3-month Follow-up
Reported as:
Median · events of condomless sex
Condomless Sex
events of condomless sexBrief Intervention (BI) With Technology ExtenderBrochure
Condomless Sex3 (2 to 4)5 (4 to 6)
SecondaryAlcohol Use Quantity

The average number of drinks in a week

Time frame:
3-month Follow-up
Reported as:
Mean · drinks per week
Alcohol Use Quantity
drinks per weekBrief Intervention (BI) With Technology ExtenderBrochure
Alcohol Use Quantity3.23 ± 3.224.00 ± 3.08
SecondaryAlcohol Use Binge Frequency

The number of drinking occasions (single day) when 4 or more drinks are consumed

Time frame:
3-month Follow-up
Reported as:
Mean · heavy episodic drinking days
Alcohol Use Binge Frequency
heavy episodic drinking daysBrief Intervention (BI) With Technology ExtenderBrochure
Alcohol Use Binge Frequency2.36 ± 3.272.00 ± 2.00

Adverse events

Collected over 3 months. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Brief Intervention (BI) With Technology Extender0/26 (0%)0/26 (0%)0/26 (0%)
Brochure0/22 (0%)0/22 (0%)0/22 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)Brief Intervention (BI) With Technology ExtenderBrochureTotal
Mean21.28 ± 2.6124.33 ± 2.9222.67 ± 3.13
Sex: Female, Male
Sex: Female, Male(Participants)Brief Intervention (BI) With Technology ExtenderBrochureTotal
Female262248
Male000
Ethnicity (NIH/OMB)
Ethnicity (NIH/OMB)(Participants)Brief Intervention (BI) With Technology ExtenderBrochureTotal
Hispanic or Latino8614
Not Hispanic or Latino171532
Unknown or Not Reported112
Race (NIH/OMB)
Race (NIH/OMB)(Participants)Brief Intervention (BI) With Technology ExtenderBrochureTotal
American Indian or Alaska Native000
Asian224
Native Hawaiian or Other Pacific Islander000
Black or African American235
White161228
More than one race235
Unknown or Not Reported426
Region of Enrollment
Region of Enrollment(participants)Brief Intervention (BI) With Technology ExtenderBrochureTotal
United States262248
07

Study locations

1 site
  • Planned Parenthood of Southern New England
    Providence, Rhode Island 02906, United States
08

References and documents

Study documents

  • Study protocol · Mar 28, 2018
  • Statistical analysis plan · Mar 28, 2018
  • Informed consent form · Oct 4, 2017

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Registry details

Key details

Study ID
NCT03323086
Lead sponsor
The Miriam Hospital
Collaborators
Planned Parenthood of Southern New England, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Responsible party
Michael P. Carey (Professor and Director, Centers for Behavioral and Preventive Medicine, The Miriam Hospital, The Miriam Hospital) — Principal investigator
First posted
Oct 26, 2017
Start date
Oct 18, 2017
Primary completion
Jun 30, 2019
Completion
Nov 1, 2019
Results posted
Jan 2, 2020
Last update
Jan 7, 2020

Study contacts

Michael P Carey, PhD
principal investigator · The Miriam Hospital

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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