An observational study in Complication of Surgical Procedure, sponsored by Assiut University. Status unknown. Open to male participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2017-10-19.
Sponsored by Assiut University · Observational
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous penile surgery as for hypospadias repair.The congenital penile curvatures (CPC) which not associated with urethral malformation is a relatively uncommon condition that may present in late adolescent or early adult life. The incidence is estimated to be 0.6 % but the incidence of clinically significant CPC is much lower, as the degree of curvature and sexual dysfunction varies widely Penile curvature may lead to inability for sexual intercourse. These cases require treatment. Acquired penile curvature its most common cause is Peyronie's disease. Peyronie's disease is a fibrotic disorder of the tunica albuginea of the corpora cavernosa that is clinically defined by the presence of a palpable, inelastic tunical plaque. PD is relatively common and affects up to 20.3% of adult men to some degree.
Surgery is gold-standard for treatment of curvature in stable PD. Surgical therapy is subdivided into three main procedures: (1) plication techniques (Penile shortening procedures), (2) grafting procedures with partial plaque excision or incision followed by defect closure with various grafts, and (3) correction of deviation with simultaneous penile prosthesis implantation in patients with ED not responding to medical therapy.
In this study results of different surgical techniques in management of penile curvature will be compared.
The type of surgery will be chosen according to the degree of curvature and penile length after meticulous preoperative assessment.
Preoperative evaluation
History of previous penile surgery.
Plication On convex side of the shaft, Allis clamps are used on the greater curvature to estimate the number and length of tissue needed for plications, nonabsorbable stitches are placed into the tunica albuginea in pairs and adjusted as needed to achieve optimal straightening. The artificial erection is then released and sutures tied.
Nesbit Technique On the convex side of the shaft, excision of horizontal ellipses of the tunica albuginea on the greater curvature (with approximately 1 mm for each 10º of curvature), Allis clamps are then applied until the desired straightening is achieved. These ellipses are excised and closed transversely in a stepwise fashion until curvature is completely corrected.
Modified Nesbit Technique On the convex side of the shaft consisted of a longitudinal incision in the tunica with transverse closure (Heineke- Mikulicz principle), The length of the incision is limited to about 1 cm to prevent excessive indentation of the penis.
Length-Preserving Techniques (Grafting Technique) On the concave border of the penile shaft tunica lengthening procedures involve incising or excising the plaque, and adding graft material to cover the defect, Excision can be avoided if the surgeon is able to perform relaxing incisions on the plaque with added grafting material. The graft (usually 20% larger than the defect) is then sutured to the tunica albuginea with separate running suture, The types of graft used are autologous buccal mucosa or dermal graft.
The patients will return to outpatient clinic after discharge by 1 month and 3 months to evaluate for the postoperative results and complications.
Statistical analysis The statistical analysis will be done using SPSS 21.0 (statistical package for the social sciences).
Ethical considerations Informed written consent will be obtained from all patients after explanation of the operative details and possible postoperative complications.
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All patients with penile curvature with failure of conservative/medical treatment (nonsurgical treatment) and patient's preference for definite results According to exclusion and inclusion criteria Attending Assiut andrology outpatient clinic.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Correcting the curvature.
Measure of any residual curvature present by using the protractor.
Time frame: 3 months postoperative
Preserving erectile function and hardness.
to show any affection of erectile function by using Interarnational index of Erectile dysfunction questionnaire.
Time frame: 4 months
Preserving penile length.
to measure penile length postoperative and compare to the preoperative length
Time frame: 3 months
Penile sensation.
To show any affection of penile sensation postoperative
Time frame: 3 months
No study locations are listed for this record.
Plan to share: No
This study is status unknown, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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