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CompletedNCT03292523WHYUpdated Apr 29, 2022

Work Productivity in Hyperventilation Syndrome

An observational study in Hyperventilation Syndrome, sponsored by University Hospital, Lille. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-04-29.

Sponsored by University Hospital, Lille · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years and older
Sex
All
01

Study summary

Hyperventilation syndrome is associated with impaired quality of life. The aim of the study is to assess the relationship between work productivity, including absenteeism and presenteeism, and the severity of hyperventilation syndrome

02

Conditions studied

  • Hyperventilation Syndrome

Keywords

  • Hyperventilation syndrome
  • Work productivity
  • Absenteeism
  • Presenteeism
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

patients with confirmed hyperventilation syndrome, virgin of any treatment.

Inclusion criteria

  • Holders of employment contracts for at least 8 days
  • Diagnosis of hyperventilation syndrome confirmed by:

Compatible symptoms and at least two symptoms reproduced by the hyperventilation challenge test: Nijmegen's score> 23 ; Demonstration of alveolar hyperventilation ( Either on rest blood and / or at rest (PaCO2 at rest \<36 mmHg and D (A-a) O2 normal; Either during the HV test (increased recovery time of the basic PETCO2 after voluntary hyperventilation (greater than 5 minutes)

Exclusion criteria

Exclusion Criteria:

  • Existence of another chronic pulmonary disease (asthma, bronchial dilation, COPD, diffuse interstitial pneumonia, neuromuscular pathology ...) or cardiac (rhythm disorder, ischemic heart disease ...) which can participate in dyspnea
  • Psychiatric illness / psychotropic treatment
  • Pregnancy
  • Patient already included in a clinical research protocol involving new therapeutics may not be included in this protocol
  • Specific physiotherapy or previous training
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (actual)
Patient registry
No

Groups and cohorts

  • Hyperventilation syndrome

    Other: questionnaire

Interventions

  • Otherquestionnaire

    Work Productivity and Activity Impairment (WPAI) Multidimensional Dyspnea Profile (MDP) Baseline Dyspnea Index (BDI), MOS-SF36, Hospital Anxiety Depression (HAD) Cognitive Failure Questionnaire (CFQ).

05

What researchers measure

Primary outcomes

  1. Association between the WPAI score and the Nijmegen score

    Time frame: At the time of diagnosis (Baseline)

Secondary outcomes

  1. Association between the WPAI score and dyspnea scales

    Time frame: At the time of diagnosis (Baseline)

  2. Association between the WPAI score and quality of life scores

    Time frame: At the time of diagnosis (Baseline)

  3. Association between the WPAI score and PaCO2

    Time frame: At the time of diagnosis (Baseline)

  4. Association between the WPAI score and the Cognitive Failure Questionnaire score

    Time frame: At the time of diagnosis (Baseline)

06

Study locations

1 site
  • Hôpital Calmette,CHU
    Lille, France
07

Registry details

Key details

Study ID
NCT03292523
Lead sponsor
University Hospital, Lille
Responsible party
Sponsor
First posted
Sep 25, 2017
Start date
Feb 6, 2018
Primary completion
Feb 23, 2021
Completion
Feb 23, 2021
Last update
Apr 29, 2022

Study contacts

Cécile Chenivesse, MD
principal investigator · University Hospital, Lille

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.

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