CClinicalTrials.gg
Active, not recruitingNCT03284593LAM-BDDUpdated Jul 30, 2020

Prognostic Factors and the Impact of Various Management of Acute Myeloid Leukemia in Real Life Condition

An observational study in Acute Myeloid Leukemia, sponsored by University Hospital, Toulouse. Active, not recruiting at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-07-30.

Sponsored by University Hospital, Toulouse · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
199
Ages
18 Years and older
Sex
All
01

Study summary

The treatment of older patients with acute myeloid leukemia that is secondary to previous myelodysplastic syndrome, myeloproliferative neoplasm, or prior cytotoxic exposure remains unsatisfactory. We compared patients treated with intensive chemotherapy or azacitidine within two centres.

02

Conditions studied

03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Diagnosis of acute myeloid leukemia between 2000 and 2014 in 2 hospitals in South of France

Eligibility criteria

Inclusion Criteria:

  • patients with acute myeloid leukemia
04

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
199 participants (actual)
Patient registry
No

Groups and cohorts

  • intensive chemotherapy group

    patients treated with intensive chemotherapy

    Drug: intensive chemotherapy

  • Azacitidine group

    patients treated with azacitidine

    Drug: Azacitidine

Interventions

  • Drugintensive chemotherapy
  • DrugAzacitidine
05

What researchers measure

Primary outcomes

  1. Survival

    Survival times

    Time frame: 2 years

06

Study locations

2 sites
  • University Hospital Bordeaux
    Bordeaux, France
  • University Hospital Toulouse
    Toulouse, 31052, France
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03284593
Lead sponsor
University Hospital, Toulouse
Responsible party
Sponsor
First posted
Sep 15, 2017
Start date
Dec 2014
Primary completion
Dec 2030 (estimated)
Completion
Dec 2030 (estimated)
Last update
Jul 30, 2020

Study contacts

Christian RECHER, MD
principal investigator · University Hospital, Toulouse

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Jul 2020. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion