ClinicalTrials.gg
RecruitingNCT07714044Updated Oct 1, 2026

Rutgers University Study of the Genetics of Blood Cancers

An observational study in Blood Cancers, Blood Cancer and Leukemia, sponsored by Rutgers, The State University of New Jersey. Recruiting at 1 site in United States. Open to participants aged 18 Years to 110 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-01.

Sponsored by Rutgers, The State University of New Jersey · Observational

From the registry’s dates

  • Started Sep 2026; still recruiting 1 month later.
Updated Oct 1, 2026Study contact changedGo to Updates ↓
Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
10,000
Ages
18 Years to 110 Years
Sex
All
01

Study summary

The goal of this study is to enroll at least 10,000 participants nationally including affecteds and unaffecteds via online study portal, collect surveys online and a saliva sample through the mail, sequence DNA, and conduct genetic analyses to identify novel variants and further study known variants associated with leukemia, lymphoma, myeloma and other blood cancers.

Read the detailed description

This is an online research study to learn more about how genes affect your risk of blood cancers. No office visit is required and in return, participants may receive information about their genetic ancestry for free. This study will increase our understanding of the genetic basis of blood cancers, which is a crucial step in drug development to improve current treatment options. We seek a diverse population because diversity among participants maximizes the usefulness of the data. Participants will use our online study portal to answer questions about their health and provide their DNA via a saliva sample using a pre-paid mailer. Participation takes approximately 20 minutes. Participants will be invited to share data from their electronic health records, but this is not required for study participation. We keep participants engaged with short monthly newsletters.

02

Conditions studied

  • Blood Cancers
  • Blood Cancer
  • Leukemia
  • Lymphoma
  • Myeloma
  • Hematologic Cancer
  • Hematologic Malignancies
  • Hematologic Neoplasm
  • Hematologic Tumors

Keywords

  • genetics
  • blood cancer
  • blood cancers
  • leukemia
  • lymphoma
  • myeloma
  • hematologic cancer
  • hematologic malignancy
  • hematologic tumor
  • hematologic neoplasm
03

In context

Hematologic Neoplasms

1,444 studies on the registry are indexed under Hematologic Neoplasms; 420 are open to participants now.

This study's planned enrollment of 10,000 is above the median of 186 across 322 observational studies indexed under Hematologic Neoplasms.

Browse Hematologic Neoplasms studies →

Lead sponsor

Rutgers, The State University of New Jersey is the lead sponsor of 506 studies on the registry; 131 are open to participants now.

Of its 39 completed or terminated interventional studies of FDA-regulated products, 31 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 110 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study population consists of anyone at least 18 years old who lives in the United States, including both individuals who have or had blood cancer and those who have not. Participants include males, females, non-binary, and all race-ethnic groups.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • age 18 years or older
  • currently living in the United States
  • have access to the internet and a computer, laptop, tablet or smartphone
  • willing to provide written for participation
  • willing to provide DNA via a saliva sample using a collection kit mailed to your home
  • willing to complete a survey with questions about health related to the study of blood cancer.

Exclusion criteria

Exclusion Criteria:

  • Not able to meet or fulfill any of the inclusion criteria
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
10,000 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Cases

    Persons with blood cancer

  • Controls

    Persons who do not have blood cancer

06

What researchers measure

Primary outcomes

  1. Genetic risk variants associated with blood cancer

    Genetic factors will be measured through whole exome sequencing and genome-wide genotyping array, and then correlated with blood cancer subtype.

    Time frame: 2 years

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No — Our study protocol does not include sharing IPD.

No publications or documents are linked to this record.

09

Updates

2 registry updates since Sep 25, 2026
Contact
Study contact's phone or email changed: r•••@rutgers.edu→r•••@rutgers.edu. See the current contact
Oct 1, 2026
Show all 2 updates
  1. Oct 1, 2026
    Contact Study contact's phone or email changed: r•••@rutgers.edu→r•••@rutgers.edu. See the current contact
  2. Sep 25, 2026
    Minor edits only
    + 1 other change: responsible party

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07714044
Responsible party
Tara Matise, Ph.D. (Distinguished Professor, Rutgers, The State University of New Jersey) — Principal investigator
First posted
Jul 20, 2026
Start date
Sep 22, 2026
Primary completion
Aug 2029 (estimated)
Completion
Aug 2029 (estimated)
Last update
Oct 1, 2026

Study contacts

Tara Matise, PhD
Contact
rugcc-blood-cancer@rutgers.edu
848-445-3125
Tara Matise, PhD
principal investigator · Rutgers University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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