An interventional study of model controlling and conventional controlling in Cerebral Revascularization and Ischemic Cerebrovascular Disease, sponsored by Xuanwu Hospital, Beijing. Status unknown at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-08-22.
Sponsored by Xuanwu Hospital, Beijing · Not applicable, Interventional, and Treatment
Objective: Referring The relation between CEA(Carotid endarterectomy) postoperative blood flow monitoring and blood pressure, and combining patient demographics and preoperative risk factors to establish an applicable individual blood pressure controlling model. By comparing with routine antihypertensive strategies through prospective randomized controlled trials , to provide the best perioperative blood pressure control standards and strategies for each patient ,thus better ensuring the safety and efficacy of CEA .
Exclusion Criteria:
an statistical model for periprocedural blood pressure control
Other: model controlling
an conventional strategy for periprocedural blood pressure control
Other: conventional controlling
control blood pressure by statistical l model with anticipate lowest peri-procedure risk
control blood pressure by conventional strategy
death
all cause death
Time frame: 30 days
ischemic stroke
Ischemic stroke is defined as an acute episode of neurological events with focal symptoms and signs, with a duration of more than 24h and confirmed by imaging.
Time frame: 30 days
cardiovascular events
Cardiovascular events were defined as: ECG presentation clearly different from preoperative myocardial ischemia, myocardial infarction, arrhythmia and cardiovascular death.
Time frame: 30 days
transient ischemic attack,TIA
transient ischemic attack, TIA is defined as: Patients with new onset of neurological symptoms and / or signs, duration \< 24 hours, MRI diffusion weighted imaging (DWI) did not find new infarcts. If MRI DWI showed new lesion, ischemic stroke was defined.
Time frame: 30 days
cerebral hemorrhage
cerebral hemorrhage including intracerebral hemorrhage, epidural or subdural hemorrhage, subarachnoid hemorrhage.
Time frame: 30 days
hyperperfusion syndrome
Hyperfusion Syndrome is defined as : 30 days after operation, new onset headache, vomiting, mental symptoms, macular edema, focal seizures, neurological dysfunction, or imaging brain edema, visible bleeding, and exception of new ischemic cerebral infarction or other causes.
Time frame: 30 days
epilepsy
epilepsy is defined as focal onset, with or without evolution to a bilateral tonic-clonic seizure, confirmed by EEG findings including interictal epileptiform discharges (IEDs), lateralized periodic discharges (LPDs; previously known as periodic lateralized epileptiform discharges \[PLEDs\]), and generalized periodic discharges (GPDs)
Time frame: 30 days
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Xuanwu Hospital, Beijing