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CompletedNCT03210597Updated Oct 12, 2018

Effects of Water-Based Exercise in Women With Metabolic Syndrome

An interventional study of Exercise in Metabolic Syndrome, sponsored by Federal University of Rio Grande do Sul. Completed. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-10-12.

Sponsored by Federal University of Rio Grande do Sul · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 10 months after the study started (first participant enrolled Aug 2016, registered Jun 2017).
Phase
Not applicable
Study type
Interventional
Enrollment
51
Allocation
Randomized
Sex
Female
01

Study summary

The objective of the present study was to compare the neuromuscular, cardiorespiratory and metabolic effects of 12 weeks of aerobic training, strength training and combined training in the aquatic environment in women with MS. For this purpose, 51 postmenopausal, sedentary and MS women were randomly divided into three intervention groups: hydro-aerobic (HA, n = 18, 63.77 ± 5.03 years), hydro-power (HF, n = 16, 61.01 ± 4.93 years) and hydro-combined (HC; n = 17; 60.52 ± 6.91). A subsample participated in eight weeks without physical exercise to characterize a control period. The three intervention groups performed two weekly sessions of 60 minutes for 12 weeks. Before and after the training period, blood tests, muscle strength tests, cardiorespiratory evaluation, functional tests and a questionnaire were performed. For statistical analysis, the Generalized Estimates Equations (GEE) model was used, using the "group" and the "time" as factors. The Bonferroni post hoc was used to locate the differences and the significance index adopted was α = 0.05.

Read the detailed description

Water-based exercise as a mode of aquatic exercise has been highlighted in the scientific literature. Research on different models of training, aerobic, muscle strength and combined (aerobic and muscle strength), have already demonstrated their beneficial effects on different physical abilities. Recent studies indicate benefits of water-based exercise for the population with metabolic diseases such as hypertension, type 2 diabetes, dyslipidemias and obesity. However, for subjects with metabolic syndrome (MS) there are few studies that investigated which training model in the aquatic environment could generate physical and metabolic improvements.

This study is characterized as a randomized clinical trial, which treated three intervention groups with physical exercise programs. A subsample participated in a period of eight weeks without physical exercise to characterize a control period. The subjects in this subsample were later randomized into the intervention groups.

02

Conditions studied

  • Metabolic Syndrome

Keywords

  • water-base exercise
03

In context

Metabolic Syndrome

1,963 studies on the registry are indexed under Metabolic Syndrome; 329 are open to participants now.

This study's planned enrollment of 51 is below the median of 60 across 1,459 interventional studies indexed under Metabolic Syndrome.

Browse Metabolic Syndrome studies →

Lead sponsor

Federal University of Rio Grande do Sul is the lead sponsor of 118 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Postmenopausal;
  • Sedentary;
  • Presented at least three positive components within the five possible to characterize the metabolic syndrome.

Exclusion criteria

Exclusion Criteria:

  • Smokers.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
51 participants (estimated)

Study arms

  • Experimental
    hydro-aerobic

    Water aerobics exercise

    Other: Exercise

  • Experimental
    hydro-power

    Resistance water exercise

    Other: Exercise

  • Experimental
    hydro-combined

    Water aerobics and resistance water exercise

    Other: Exercise

Interventions

  • OtherExercise

    The subjects performed training in aquatic environment

06

What researchers measure

Primary outcomes

  1. Systolic and diastolic blood pressure

    mmHg

    Time frame: 12 weeks

Secondary outcomes

  1. Strength tests: Maximum dynamic muscle strength

    One repetition test: how many kilograms the subject is able to withstand on a repetition of elbow flexion and knee extension exercise

    Time frame: 12 weeks

  2. EMG test

    Maximum isometric amplitude of the electromyographic signal of the vastus lateralis and rectus femoris muscles

    Time frame: 12 weeks

  3. Time Up and go test

    How long (in seconds) the subject needs to lift from a chair, walk 2.44 meters, and sit in a chair again

    Time frame: 12 weeks

  4. Sit and Stand test

    How often in 30 seconds the subject is able to get up and sit on a chair.

    Time frame: 12 weeks

  5. Triglyceride levels

    blood test: mg/dl

    Time frame: 12 weeks

  6. HDL cholesterol levels

    blood test: mg/dl

    Time frame: 12 weeks

  7. Fasting blood glucose levels

    blood test: mg/dl

    Time frame: 12 weeks

  8. Waist circumference

    centimeters

    Time frame: 12 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 12, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03210597
Lead sponsor
Federal University of Rio Grande do Sul
Responsible party
Luiz Fernando Martins Kruel (Doctor, Federal University of Rio Grande do Sul) — Principal investigator
First posted
Jul 7, 2017
Start date
Aug 1, 2016
Primary completion
Dec 28, 2016
Completion
Oct 10, 2018
Last update
Oct 12, 2018

Study contacts

Luiz F. Martins Kruel
study director · Federal Universty of Rio Grande do Sul

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.

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