An interventional study of Seeking Safety and CBT for Pathological Gambling in Gambling Disorder, Trauma, Psychological and Problem Gambling, sponsored by University of Windsor. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-03-30.
Sponsored by University of Windsor · Not applicable, Interventional, and Treatment
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Among 38 studies in Gambling with a site in United States — 4 open to participants now, 4 under way, none of them phase 3. Gambling · United States.
Among the 38 studies in Gambling with a site in United States, this one is the 18th largest by enrollment of the 33 interventional ones that give a count, is one of 2 that started in 2016, is one of 17 with no phase, and was the 30th registered.
158 studies on the registry are indexed under Gambling; 42 are open to participants now.
Browse Gambling studies →4 of the 38 studies in Gambling with a site in United States are open now. Recruiting first, the newest first:
Yale University · Sites in United States
Ages 18+
University of Virginia · Sites in United States
Ages 18–60
Veterans Recovery Network Inc. · Sites in United States
Ages 17–99 · Healthy volunteers
East Tennessee State University · Sites in United States
Ages 18+
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 24 Gambling studies recruiting now, 14 (58%) set no upper age limit and 10 (42%) stop at 75 or younger; 1 takes children under 18; 5 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · no healthy volunteers.
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38 studies; the count open now beside each. This study's row is marked.
First in 1998; this study’s year is marked. 2 started in 2016.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 65 is close to the median of 66 across 128 interventional studies indexed under Gambling.
Median enrollment 66 across the 33 interventional studies, 57 across the 5 observational. Of the 32 that completed or were terminated, 9 (28%) have results posted.
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2 of 38 have an industry lead sponsor. The 10 most frequent:
University of Windsor is the lead sponsor of 9 studies on the registry; 2 are open to participants now.
University of Windsor has 1 study filed under Gambling — fewer than ten, so there is no comparison to draw.
1 of the studies in Gambling with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07016100East Tennessee State UniversityContingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder | 2026-12-01 |
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Among the 38 studies in Gambling with a site in United States, from their registry updates:
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This randomized controlled trial examines the efficacy of two behavioral therapies. Seeking Safety, which addresses co-occurring problem gambling (PG) and posttraumatic stress disorder (PTSD), is being compared to Cognitive-Behavioral Therapy for PG, which addresses only PG. Both models are delivered via telehealth.
Our key study question is whether an integrated focus on PG and PTSD (Seeking Safety; SS) offers a useful new option for clinical care compared to a purely problem gambling approach (Cognitive-Behavioral Therapy for PG; CBT-PG). This question-the impact of integrated versus non-integrated treatment for co-occurring disorders-is one of the key issues in the field currently and has never been studied in relation to PG and PTSD.
Our aims are:
Our hypotheses are: (a) SS will do no worse than CBT-PG on the primary PG outcomes as both treatments are designed to address addiction; i.e., both will show improvement from baseline to end of treatment and maintenance of gains through the followup. (b) SS will show superior results on trauma symptoms as SS is designed to address those, whereas CBT-PG is not.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Behavioral therapy for trauma and addiction.
Behavioral: Seeking Safety
Behavioral therapy for gambling problems.
Behavioral: CBT for Pathological Gambling
Seeking Safety (SS) is a present-focused, evidence-based cognitive-behavioral therapy for trauma and/or addiction. It offers safe coping skills and education relevant to both problem areas.
Cognitive Behavior Therapy for Pathological Gambling (CBT-PG) is an evidence-based therapy for gambling problems. It focuses on cognitive correction, problem solving, social skills and relapse prevention.
Money spent gambling
Change from baseline in amount of money spent gambling in the past month
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
Number of gambling sessions
Change from baseline in number of days in the past month during which gambling occurred
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
PTSD Checklist (PCL) scores
Posttraumatic stress disorder (PTSD) symptoms
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
Trauma Symptom Checklist 40
Change in baseline in broad trauma-related symptoms
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
Brief Symptom Inventory-18 scores
Change from baseline in general psychiatric symptoms
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
Brief Addiction Monitor scores
Change from baseline in substance use and associated problems
Time frame: 6-weeks (mid-treatment), 12-weeks (end-of-treatment), and 12-months
Plan to share: Undecided
No publications or documents are linked to this record.
Ran from Oct 2016 to primary completion in Jun 2021, 56 months.
Of 47 non-industry interventional studies with no phase under Gambling, half reached primary completion within 16 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 51. This study's 56 months is above that.
Counting every sponsor, half of 47 studies reached it within 16 months; a quarter within 10 and three quarters within 51.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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University of Windsor