An observational study in Embolic Stroke of Undetermined Source and Ischemic Stroke, sponsored by Fondation Ophtalmologique Adolphe de Rothschild. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-06-22.
Sponsored by Fondation Ophtalmologique Adolphe de Rothschild · Observational
The ESUS concept was introduced recently to describe a non-lacunar stroke of undetermined etiology. The following etiological workup is required in this setting: head CT or MRI, 12-lead ECG, transthoracic echocardiography, continuous cardiac monitoring for at least 24 hours after stroke, vascular imaging (ultrasound, magnetic resonance angiography, CT angiography, catheter angiography). Transesophageal echocardiography (TEE) is considered not to be required.
However, aortic arch atheroma as diagnosed by TEE in the setting of recent ischemic stroke is a major aortic source of embolism, as supported by numerous well conducted studies. The European Association of Echocardiography considers that TEE is the gold standard for the diagnosis and the characterization of aortic atheroma. It is also the method of choice for the diagnosis of infectious endocarditis.
The aim of this work was to evaluate the rate of patients with a therapeutic modification induced by TEE (mainly anticoagulation and surgery), in consecutive patients admitted with ESUS at our institution stroke unit.
Patients followed for ichemic stroke meeting embolic source of unknown source criteria
Exclusion Criteria:
therapeutic modification after transesophageal echocardiography
proportion of patients with a therapeutic modification (mainly anticoagulation and surgery)
Time frame: 24 hours after TEE
This study is completed, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.
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Fondation Ophtalmologique Adolphe de Rothschild