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CompletedNCT03072654Updated Mar 7, 2017

Tracheal Anatomy After Thyroidectomy

An observational study in Goiter, Nodular, sponsored by University of Southern Denmark. Completed. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2017-03-07.

Sponsored by University of Southern Denmark · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
72
Ages
20 Years to 80 Years
Sex
All
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Study summary

The investigators aimed at investigating the effects of thyroidectomy on tracheal anatomy and airflow in patients with benign nodular goiter, employing a prospective observational study.

Magnetic resonance images of the neck and respiratory flow-volume curves were performed prior to and six months following surgery. Tracheal and thyroid volumes, smallest cross-sectional area of the trachea (SCAT), tracheal narrowing, tracheal deviation and tracheal encirclement by the thyroid were evaluated. Through flow-volume curves respiratory function, including both in- and expiration, was evaluated.

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Conditions studied

  • Goiter, Nodular

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03

In context

Goiter, Nodular

19 studies on the registry are indexed under Goiter, Nodular; 6 are open to participants now.

Browse Goiter, Nodular studies →

Lead sponsor

University of Southern Denmark is the lead sponsor of 336 studies on the registry; 46 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients referred for thyroidectomy for symptomatic benign nodular goiter

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Reads and write Danish

Exclusion criteria

Exclusion Criteria:

  • Suspected or present
  • Neuromuscular disease
  • Prior surgery to the neck
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
72 participants (actual)
Patient registry
No

Interventions

  • ProcedureThyroidectomy

    Remove the nodular goiter on the neck by thyroidectomy (standard procedure)

06

What researchers measure

Primary outcomes

  1. Changes in tracheal anatomy

    Change in tracheal narrowing (cross sectional area of the trachea at the goiter level compared to cross-sectional area of the trachea at the carina)

    Time frame: 6 months follow-up

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Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Brinch FA, Dossing H, Nguyen N, Bonnema SJ, Hegedus L, Godballe C, Sorensen JR. The Impact of Esophageal Compression on Goiter Symptoms before and after Thyroid Surgery. Eur Thyroid J. 2019 Jan;8(1):16-23. doi: 10.1159/000493542. Epub 2018 Oct 17. PubMed 30800637 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 7, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03072654
Responsible party
Jesper Roed Sorensen (PhD Fellow, University of Southern Denmark) — Principal investigator
First posted
Mar 7, 2017
Start date
Nov 1, 2014
Primary completion
Mar 1, 2017
Completion
Mar 2, 2017
Last update
Mar 7, 2017

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2017. You cannot join it, but the record below documents what was studied.

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Discussion

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