An interventional study of Brief intervention in Alcohol Use Disorder and Critically Ill, sponsored by University of Helsinki. Terminated at 3 sites in Finland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-12-10.
Sponsored by University of Helsinki · Not applicable, Interventional, and Treatment
Patients non-electively admitted to intensive care units (ICUs) will be screened for eligibility. The investigators will include adult patients with risk level alcohol use, defined by AUDIT-C score (>5 for females, >6 for males). Informed consent will be obtained from the patient in the end or shortly after the ICU treatment, when they have regained sufficient cognitive function. 600 patients will be randomized to receive either routine treatment or a brief intervention (BI). The BI includes a 20 minute discussion with pre-educated study personnel, option to discussion with a social worker and written material. Primary outcome measure is the amount of alcohol used during the preceding week (g/week), at 6 and 12 months after study entry. The information will be obtained 1)in an interview by a study team member blinded for the intervention arm at 6 months 2) A letter of a telephone interview at 12 months. AUDIT score, EQ-5D and mortality will also be recorded.
An interim analysis by an external reviewer will be performed after the primary outcome has been recorded for 200 patients,
1,634 studies on the registry are indexed under Alcoholism; 329 are open to participants now.
This study's enrollment of 237 is above the median of 88 across 1,395 interventional studies indexed under Alcoholism.
Browse Alcoholism studies →University of Helsinki is the lead sponsor of 132 studies on the registry; 19 are open to participants now.
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Exclusion Criteria:
Treatment as usual and discussion according to the treating clinicians in the hospital
Patients receive a brief intervention, including a short discussion, opportunity for an appointment with a social worker and written information about effects of alcohol on health and contact information for seeking additional support
Behavioral: Brief intervention
A 15-20minute discussion about the patients alcohol use and its association with current health conditions, option for a discussion with social worker and written material (information about how alcohol affects health and contact details for seeking more support)
Also known as: Mini-intervention
Reported total amount of alcohol consumed during preceding week
The patients are interviewed and the amount of alcohol consumed during the last week is recorded and converted in grams
Time frame: 6 months after study enrollment
Reported total amount of alcohol consumed during preceding week
The patients are interviewed and the amount of alcohol consumed during the last week is recorded and converted in grams
Time frame: 12 months after study enrollment
Change in AUDIT score
The AUDIT score will be filled in an interview and compared with the initial score obtained on study admission
Time frame: 6 months after study enrollment
Change in AUDIT score
The AUDIT score will be filled in a telephone interview or by mailed questionnaire and compared with the initial score obtained on study admission
Time frame: 12 months after study enrollment
Mortality
Survival of the patients will be obtained from Statistics Finland
Time frame: One year after study enrollment
Quality of life
A structured questionnaire EQ-5D will be mailed or filled in a telephone interview and the EQ-5D will be compared between the groups
Time frame: One year after study enrollment
Plan to share: No
This study is terminated, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.
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