An observational study in TBI (Traumatic Brain Injury), sponsored by Sheba Medical Center. Recruiting at 1 site in Israel. Open to participants aged 9 Years to 18 Years. Per ClinicalTrials.gov, last updated 2023-11-24.
Sponsored by Sheba Medical Center · Observational
This project will combine the data collected from structural and functional MRI scans and neuropsychology performance post-TBI in children. Patients will be followed for a year, in order to examine the brain and cognitive recovery post head injury.
Traumatic brain injury in childhood has an cumulative effect that leads to impairments in cognitive functions such as deficits in memory, executive functions and attention. The cognitive impairment is the main cause of disabilities in the injured population, and has a different effect depending on the type and severity of the injury.
Imaging after brain trauma serves as a useful diagnostic tool in identifying the head trauma's results. Therefore, in recent years, using imaging methods, studies have tried to find measures which will be able to predict the functional outcome after brain injury in children, and assist in developing a personalized rehabilitation program. The combination of advanced imaging techniques with neuropsychological assessment within the early stage of the injury and during a year of followup, will allow us to establish the relationship between those measures and the functional recovery result of the children. This multi-analysis will enable us to have a deeper understanding of the neuroplasticity process and the functional recovery after brain injury in the developing young brain.
2,113 studies on the registry are indexed under Brain Injuries; 385 are open to participants now.
This study's planned enrollment of 60 is below the median of 100 across 690 observational studies indexed under Brain Injuries.
Browse Brain Injuries studies →Sheba Medical Center is the lead sponsor of 660 studies on the registry; 63 are open to participants now.
Counted across the registry records on this site, refreshed daily.
study population will include 1 group of subjects: group 1: young subjects, age 9-18, after traumatic brain injury
Exclusion Criteria:
Functional MRI
fMRI brain activation to a cognitive tasks
Time frame: 12 months
Structural MRI
MRI Structural changes using different methods
Time frame: 12 months
neuropsychological tests
Cognitive scores on neuropsychological testing
Time frame: 12 months
Associations between the cognitive performance and the imaging methods
Time frame: 12 months
Plan to share: Undecided
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