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CompletedNCT03032133Updated Feb 12, 2019

Pain Control After Total Knee Arthroplasty

An interventional study of Regional pain control and Local pain control in Knee Osteoarthritis, sponsored by Technische Universität Dresden. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-02-12.

Sponsored by Technische Universität Dresden · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 11 months after the study started (first participant enrolled Feb 2016, registered Jan 2017).
Phase
Not applicable
Study type
Interventional
Enrollment
140
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Patients are randomized to receive pain control after Total Knee Arthroplasty with either a regional pain catheter or a local intraarticular pain catheter. Pain, analgetic use and mobility is asessed.

02

Conditions studied

  • Knee Osteoarthritis

Keywords

  • Total Knee Arthroplasty
  • Total Knee Replacement
  • Outcome
  • Results
  • Pain
03

In context

Osteoarthritis, Knee

3,391 studies on the registry are indexed under Osteoarthritis, Knee; 628 are open to participants now.

This study's planned enrollment of 140 is above the median of 69 across 2,808 interventional studies indexed under Osteoarthritis, Knee.

Browse Osteoarthritis, Knee studies →

Lead sponsor

Technische Universität Dresden is the lead sponsor of 247 studies on the registry; 46 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Indication to Total Knee Arthroplasty
  • Signed informed consent

Exclusion criteria

Exclusion Criteria:

  • Chronic pain
  • Allergy against local anaesthetics
  • Not understanding study or questionnaires
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
140 participants (estimated)

Study arms

  • Active comparator
    Regional pain control

    Regional pain catheter

    Procedure: Regional pain control

  • Experimental
    Local pain control

    Local intraarticular pain catheter

    Procedure: Local pain control

Interventions

  • ProcedureRegional pain control

    Regional pain catheter

  • ProcedureLocal pain control

    Local intraarticular pain catheter

06

What researchers measure

Primary outcomes

  1. pain

    Pain on Visual Analog Scale

    Time frame: daily until day 7 after surgery

Secondary outcomes

  1. analgetics

    Use of additional analgetics

    Time frame: daily until day 7 after surgery

  2. Mobility

    grade of mobility

    Time frame: daily until day 7 after surgery

  3. Function

    Knee Society Score

    Time frame: preoperative, 3 month, 1 year

  4. Patient reported outcome

    Oxford Knee Score

    Time frame: preoperative, 3 month, 1 year

  5. Quality of Life

    EQ 5D

    Time frame: preoperative, 3 month, 1 year

07

Study locations

1 site
  • Universitätsklinikum Carl Gustav Carus
    Dresden, 01307, Germany
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 12, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03032133
Collaborators
Mathys Ltd Bettlach
Responsible party
Sponsor
First posted
Jan 26, 2017
Start date
Feb 2016
Primary completion
Dec 2017
Completion
Dec 2018
Last update
Feb 12, 2019

Study contacts

Jörg Lützner, MD
principal investigator · TU Dresden

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

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