CompletedNCT02930577TASUUpdated Oct 12, 2016

Treatment Adherence in Substance Users

An observational study in Substance-Related Disorders, sponsored by Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-10-12.

Sponsored by Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Observational

Study type: Observational
Time perspective: Retrospective
Enrollment: 216
Ages: 18 Years and older
Sex: All

Study summary

This study evaluates the factors associated with treatment adherence in substance users. Differences in the level of adherence to treatment according to patient-related factors, addiction and treatment are analyzed. The individual effect of each factor on treatment adherence is assessed.

Read the detailed description

INTRODUCTION: Treatment dropout is an unsolved problem in the addiction process which makes frequent the failure of the addiction therapy. Research shows that the majority of dropouts occur during the first weeks of the treatment. These are the most serious ones because they have the worst prognosis. Some factors, related to the patients and the therapy, have been associated with treatment dropout but the diversity of studied variables, the heterogeneity of patients and the sparse population of many studies, hampers external validity and comparison of results.

OBJECTIVES: Analyze the treatment adherence of an outpatient treatment program for addicts. Identify factors associated with treatment adherence in substance users.

MATERIAL AND METHODS: Observational, analytical, longitudinal and retrospective study in substance users who completed addiction treatment between November 2013 and January 2016. Treatment adherence is measured in terms of medical discharge, regular attendance at activities and success in the NOC indicators. Differences in the level of adherence to treatment according to patient-related factors, addiction and treatment are analyzed. The individual effect of each factor on treatment adherence is assessed.

Conditions studied

Substance-Related Disorders

Browse trials for

Keywords

treatment adherence
outpatient treatment
drug dependence

In context

Substance-Related Disorders

2,124 studies on the registry are indexed under Substance-Related Disorders; 393 are open to participants now.

This study's enrollment of 216 is below the median of 250 across 296 observational studies indexed under Substance-Related Disorders.

Browse Substance-Related Disorders studies →

Lead sponsor

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau is the lead sponsor of 335 studies on the registry; 64 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years and older
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

Substance users who completed addiction treatment between November 2013 and January 2016.

Inclusion criteria

Clinical diagnosis of Substance-Related Disorders
Treatment for drug dependency

Exclusion criteria

Exclusion Criteria:

Admission for detoxification treatment.

Study design

Time perspective: Retrospective
Enrollment: 216 participants (actual)
Patient registry: No
Biospecimen retention: Samples without dna

What researchers measure

Primary outcomes

treatment adherence
Good adherence: if the patient complete the treatment, attends health professionals sessions and/or gets a sufficient score in objectives nursing. Bad-adherence: if the patient not complete the treatment.
Time frame: two month

Secondary outcomes

gender
options: male or female.
Time frame: two months
age
Time frame: two months
work situation
options: unemployed, worker, pensioner or student.
Time frame: two months
cohabitation
options: alone, with parents or with the couple and sons
Time frame: two months
family support
options: no support, support, support and groups
Time frame: two months
all mental disorders of DSM-IV (Diagnostic and Statistical Manual of mental Disorders)
Time frame: two months
all drugs
Time frame: two months
Self-esteem level according to the Rosenberg Self-Esteem questionnaire.
options: high, medium or low self-esteem level.
Time frame: two months

Study locations

No study locations are listed for this record.

References and documents

Publications

López Goñi JJ, Fernández-Montalvo J, Arteaga A. El abandono (dropout) en el Tratamiento de la Adicción: Explorando las Características de los Pacientes. Am J Addict. 2011;(21):78-85.
Zamora YR. Predicción del abandono del tratamiento en adictos mediante el cuestionario VPA-30. Revista del Hospital Psiquiátrico de La Habana. 2014;11(2).
Sanchez-Hervas E, Secades-Villa R, Gomez FJ, Romaguera FZ, Garcia-Rodriguez O, Yanez EM, Frances MC, Fernandez GG. [Treatment dropout in cocaine addicts]. Adicciones. 2010;22(1):59-64. Spanish. PubMed 20300715 ↗
Valero-Aguayo L, Ortiz-Tallo M, Parra-García MM, Jiménez-Guerra M. Valoración de resultados y perfil psicosocial de un programa de rehabilitación de personas con drogodependencias. Anales de Psicología. 2013;29(1):38-47.
Fernández-Montalvo J, López Goñi JJ, Landa N, Illescas C, Lorea, I, Zarzuela, A. Trastornos de personalidad y abandonos terapéuticos en pacientes adictos: resultados en una comunidad terapéutica. Int J Clin Health Psychol. 2004; 4(2): 271-283.
Llinares Pellicer MC, Palau Munoz C, Albiach Catala C, Santos Diez P. [Predictive variables of adherence to treatment in alcoholics]. Actas Esp Psiquiatr. 2002 Nov-Dec;30(6):370-5. Spanish. PubMed 12487947 ↗
Garcia-Rodriguez O, Secades-Villa R, Alvarez Rodriguez H, Rio Rodriguez A, Fernandez-Hermida JR, Carballo JL, Errasti Perez JM, Al-Halabi Diaz S. [Effect of incentives on retention in an outpatient treatment for cocaine addicts]. Psicothema. 2007 Feb;19(1):134-9. Spanish. PubMed 17295995 ↗
Albiach C, Llinares MC, Palau C, Santos P. Adherencia en heroinómanos: la potencia predictiva de los estadios de cambio evaluados durante la admisión al tratamiento. Adicciones. 2000;12(2):225-234.
Olmos-Espinosa R, Madoz-Gúrpide A, Ochoa E. Situación al año de los adictos a opiáceos que siguieron tratamiento ambulatorio tras desintoxicación hospitalaria. Adicciones. 2001;13(2):173-8.
Albiach C, Palau C, Llinares C, Santos P. Estudio sobre la adherencia al tratamiento en sujetos con adicción a diferentes sustancias que acuden a servicios ambulatorios. En: V Encuentro Nacional sobre drogodependencias y su enfoque comunitario; 1998; Chiclana de la Frontera, Cádiz, p. 57-70.
Herrera JM, Barberán M, Yumar T. La adherencia al tratamiento en una Unidad de Atención a las Drogodependencias (UAD). Trabajo Social y Salud. 2008; (61):155-182.
López-Goñi JJ, Fernández-Montalvo J, Illescas C, Landa N, Lorea I. Razones para el abandono del tratamiento en una comunidad terapéutica. Trastor Adict. 2008;10(2):104-111.
Domínguez-Martín AL, Miranda-Estribí MD, Pedrero-Pérez EJ, Pérez-López M, Puerta-García C. Estudio de las causas de abandono del tratamiento en un centro de atención a drogodependientes. Trastor Adict. 2008;10(2):112-120.
Silva Lento AF, Cerqueira AM, Rocha Costa OC. Programa de deshabituación. ¿Cuáles son los factores que llevan al dropout? Revista española de drogodependencias. 2004; (1):62-70.
Roncero C, Rodriguez-Cintas L, Barral C, Fuste G, Daigre C, Ramos-Quiroga JA, Casas M. Treatment adherence to treatment in substance users referred from Psychiatric Emergency service to outpatient treatment. Actas Esp Psiquiatr. 2012 Mar-Apr;40(2):63-9. Epub 2012 Mar 1. PubMed 22508071 ↗
Sirvent C, Villa M, Blanco P, Rivas C, Linares MP, Quintana L. Predicción del abandono (vs. éxito) terapéutico en adicciones. (Presentación del cuestionario VPA-30 (c Sirvent, 2009), de variables predictores de abandono y adherencia al tratamiento en adicciones). Interpsiquis 2010.
Martinez-Gonzalez JM, Albein-Urios N, Verdejo-Garcia A, Lozano-Rojas O. [Differential aspects of treatment dropout risk in cocaine dependent patients with and without personality disorders]. Adicciones. 2014;26(2):116-25. Spanish. PubMed 25288259 ↗
Roncero C, Gomez-Baeza S, Vazquez JM, Teran A, Szerman N, Casas M, Bobes J. Perception of Spanish professionals on therapeutic adherence of dual diagnosis patients. Actas Esp Psiquiatr. 2013 Nov-Dec;41(6):319-29. Epub 2013 Nov 1. PubMed 24203504 ↗

Individual participant data

Plan to share: Undecided

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Oct 12, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02930577
Lead sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Responsible party: Sponsor
First posted: Oct 12, 2016
Start date: Oct 2015
Primary completion: May 2016
Completion: Aug 2016
Last update: Oct 12, 2016

Oversight

Data monitoring committee: Yes

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2016. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Substance-Related Disorders→

Other studies from this sponsor

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Start the discussion