CClinicalTrials.gg
Status unknownNCT02895256Updated Mar 20, 2020

Long-term Prognosis of Cluster Headache: a Retrospective Cohort Study

An observational study in Cluster Headache and Disease Course, sponsored by Samsung Medical Center. Status unknown at 1 site in Korea, Republic of. Per ClinicalTrials.gov, last updated 2020-03-20.

Sponsored by Samsung Medical Center · Observational

The sponsor has not verified this record recently (last verified Mar 2020), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
70
Sex
All
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Study summary

Cluster headache is a syndrome characterized by disabling headache and accompanying autonomic symptoms. Despite cluster headache is called "suicide headache", its natural history has not been well investigated. The investigators aimed to investigate its disease course, overall prognosis, and treatment pattern in retrospective cohort.

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Conditions studied

  • Cluster Headache
  • Disease Course
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In context

Cluster Headache

116 studies on the registry are indexed under Cluster Headache; 27 are open to participants now.

This study's planned enrollment of 70 is close to the median of 70 across 29 observational studies indexed under Cluster Headache.

Browse Cluster Headache studies →

Lead sponsor

Samsung Medical Center is the lead sponsor of 980 studies on the registry; 146 are open to participants now.

Of its 7 completed or terminated interventional studies of FDA-regulated products, 1 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with cluster headache

Inclusion criteria

  • Patients who were diagnosed as cluster headache
  • More than 5 years after the first visit

Exclusion criteria

Exclusion Criteria:

  • Subjects who refused the telephone visit
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
70 participants (estimated)
Patient registry
No

Interventions

  • DrugAny treatment for cluster headache
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What researchers measure

Primary outcomes

  1. overall prognosis

    active disease: at least one bout within the past 5 years Remission: no headache for 5 years and twice of the usual remission period

    Time frame: at least 5 years after the first visit

  2. Changes in the length of active/inactive periods

    Time frame: at least 5 years after the first visit

  3. Changes in seasonal and diurnal predilections

    Time frame: at least 5 years after the first visit

  4. Changes in autonomic symptoms

    Time frame: at least 5 years after the first visit

  5. Changes in treatment responses

    Time frame: at least 5 years after the first visit

Secondary outcomes

  1. Any depression

    Time frame: at least 5 years after the first visit

  2. Any suicidal thoughts (active/passive), plans, and attempts

    ictal vs interictal

    Time frame: at least 5 years after the first vis

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Study locations

1 of 1 sites recruiting
  • Samsung Medical Center
    Seoul, Korea, Republic of
    Recruiting
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 20, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02895256
Lead sponsor
Samsung Medical Center
Responsible party
Chin-Sang Chung (MD, PhD, Professor of neurology, Samsung Medical Center) — Principal investigator
First posted
Sep 9, 2016
Start date
Apr 2016
Primary completion
Apr 2021 (estimated)
Completion
Apr 2021 (estimated)
Last update
Mar 20, 2020

Study contacts

Mi Ji Lee, MD
Contact
mirony.lee@gmail.com
82-2-3410-1895
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.

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