An interventional study of neurologic and neuropsychological evaluation in Brain Ischemia, sponsored by Hospices Civils de Lyon. Completed at 1 site in France. Open to participants aged 70 Years and older. Per ClinicalTrials.gov, last updated 2017-11-20.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Basic science
Ischemic strokes are one of the leading causes of handicap and death in elderly people in France.
Cognitive reserve (CR) is an active model, defined as a function of lifetime intellectual activities and other environmental factors that explain differential susceptibility to functional impairment in the presence of pathology or other neurological insult. CR is estimated using variables for cognitive activity: years of education, professional status, socioeconomic status... Furthermore, brain reverse (BR) is a passive and quantitative model that depend on brain size and other quantitative aspects of the brain that explain differential susceptibility to functional impairment in the presence of pathology.
Firstly, volume and localization of ischemic strokes have a great impact on CR and BR due to brain injury. On the other hand, CR influences the severity and the expression of cognitive diseases.
The investigators realize a prospective study in order to assess the impact of CR and BR on cognitive prognosis after a right middle cerebral artery ischemic stroke in elderly patients.
353 studies on the registry are indexed under Brain Ischemia; 69 are open to participants now.
This study's enrollment of 20 is below the median of 60 across 213 interventional studies indexed under Brain Ischemia.
Browse Brain Ischemia studies →Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Other: neurologic and neuropsychological evaluation
cognitive prognosis, cognitive reserve, brain volume will be studied on patients with scale, questionnaire, magnetic resonance imaging
evaluation of cognitive prognosis
measure will be performed with the Mattis dementia rating scale
Time frame: one year post Ischemic stroke
Volume of leucoencephalopathy
measure will be performed with a MRI
Time frame: one year post Ischemic stroke
volume of hippocampic
measure will be performed with a MRI
Time frame: one year post Ischemic stroke
brain injury
measure will be performed with a MRI
Time frame: one year post Ischemic stroke
volume of ischemic stroke
measure will be performed with a MRI
Time frame: one year post Ischemic stroke
evaluation of cognitive reserve
measure will be performed with the Cognitive reserve index questionnaire
Time frame: one year post Ischemic stroke
This study is completed, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon