CClinicalTrials.gg
Status unknownNCT02723643Updated Mar 30, 2016

Potential Associated Factors of Uncontrolled Hypertension

An observational study in Hypertension,Essential, sponsored by Guangdong Provincial People's Hospital. Status unknown at 1 site in China. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2016-03-30.

Sponsored by Guangdong Provincial People's Hospital · Observational

The sponsor has not verified this record recently (last verified Mar 2016), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
2,000
Ages
50 Years to 80 Years
Sex
All
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Study summary

The incidence and prevalence of hypertension is increasing while the controlled rate is extremely low in China. A substantial percentage of participants with uncontrolled hypertension are correctable if potential associated factors are identified and corrected. Therefore, it is clinically relevant to investigate and identify these potential associated factors of uncontrolled hypertension so as to increase controlled rate and reduce hypertension-associated health and economic burdens in the future. Investigators plan to conduct a prospective registry study in a single-center to initially investigate the potential associated factors of uncontrolled hypertension in cardiovascular outpatient department. Furthermore, investigators plan to evaluate the effects of potential associated factors correction on hypertension controlled rate and cardiovascular outcomes.

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Conditions studied

  • Hypertension,Essential

Keywords

  • Hypertension
  • Essential hypertension
  • Blood pressure
  • Cardiovascular diseases
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In context

Hypertension

6,687 studies on the registry are indexed under Hypertension; 964 are open to participants now.

This study's planned enrollment of 2,000 is above the median of 210 across 1,358 observational studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Guangdong Provincial People's Hospital is the lead sponsor of 231 studies on the registry; 101 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Outpatient populations with clinic systolic and/or diastolic blood pressure above 140 and/or 90 mm Hg treating with 3 different classes of anti-hypertensive drugs (not necessarily including diuretic).

Inclusion criteria

  • Clinic systolic and/or diastolic blood pressure above 140 and/or 90 mm Hg treating with 3 different classes of anti-hypertensive drugs (not necessarily including diuretic).

Exclusion criteria

Exclusion Criteria:

  • Known secondary hypertension,
  • Pregnant women,
  • Chronic kidney disease (CKD) 3 or higher,
  • Has a history of connective tissue diseases,
  • Has a history of any type of cancer,
  • Cognitive disorder which could not finish home blood pressure monitoring,
  • Has a history of coronary heart disease,ischemic stroke,transient ischemic attack or heart failure.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
2,000 participants (estimated)
Target follow-up
1 Year
Patient registry
Yes
Biospecimen retention
Samples with dna
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What researchers measure

Primary outcomes

  1. Hypertension controlled rate in participants after potential associated factors are corrected

    Participants with uncontrolled hypertension (SBP and/or DBP \>=140 and/or 90 mm Hg) treating with 3 or more anti-hypertensive drugs (not necessarily including diuretic) in outpatient department will under assessment of hypertension controlled rate 1 month later after initial investigation of potential associated factors. Based on these findings, investigators will give instructions to participants how to correct those potential associated factors and follow-up participants via telephone or outpatient visit 1 month later to assess whether these corrections could help increase hypertension controlled rate. Participants will be required to record home blood pressure measurements every day, and average home SBP and DBP will be calculated 1 month later. If average home SBP/DBP \< 135/85 mm Hg then participants will be considered as controlled-case, otherwise uncontrolled case.

    Time frame: Up to 1 month

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Study locations

1 of 1 sites recruiting
  • Guangdong Cardiovascular Institute,Guangdong General Hospital
    Guangzhou, Guangdong 510080, China
    • Yingling Zhou, MD · Contact · zylgdh123@sina.com · 86-20-83827812-10528
    • Anping Cai, MD · Contact · caianping1983@hotmail.com · 8615989267312
    • Yingqing Feng, MD · Principal investigator
    • Qi Zhong, MD · Sub investigator
    • Xida Li, MD · Sub investigator
    • Dan Zhou, MD · Sub investigator
    • Xueju Yu, MD · Sub investigator
    • Huiming Yu, MD · Sub investigator
    • Yujin Mo, MD · Sub investigator
    • Ying Zhang, MD · Sub investigator
    Recruiting
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02723643
Lead sponsor
Guangdong Provincial People's Hospital
Responsible party
Sponsor
First posted
Mar 30, 2016
Start date
Jan 2016
Primary completion
Dec 2018 (estimated)
Last update
Mar 30, 2016

Study contacts

Anping Cai, MD
Contact
caianping1983@hotmail.com
8615989267312
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2016. You cannot join it, but the record below documents what was studied.

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