An interventional study of Hydrocortisone and Saline in Intussusception, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to participants aged 3 Months to 4 Years. Per ClinicalTrials.gov, last updated 2024-08-27.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post operative. Treatment of intussusception must start with medical resuscitation, then radiological or operative reduction of intussusception.
Our surgery team has used hydrocortisone with the medical resuscitation to improve the success rate of pneumatic reduction and decrease the number of reduction trials.
Experimental group will be given single dose IV Hydrocortisone 10 mg/kg with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured.
Control group will be given Saline 100 ml IV single injection with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured.
31 studies on the registry are indexed under Intussusception; 6 are open to participants now.
This study's planned enrollment of 80 is close to the median of 78 across 16 interventional studies indexed under Intussusception.
Browse Intussusception studies →Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Hydrocortisone IV 10 mg/kg with Resuscitation before attempting reduction, single dose with Resuscitation before attempting reduction
Drug: Hydrocortisone
Saline IV 100 ml with Resuscitation before attempting reduction, single dose with Resuscitation before attempting reduction
Drug: Saline
10 mg/kg with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
Also known as: Solu-Cortef
100 ml with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
Also known as: sodium chloride 0.9%
Success of Pneumatic Reduction
Comparing number of Successful Pneumatic Reductions in both groups
Time frame: 1 Hour
Reducing number of trials of Pneumatic Reduction
Comparing average number of Pneumatic Reduction trials between both groups
Time frame: 2 Hours
Reducing complications
Comparing number of complications in both groups
Time frame: 2 Hours
Plan to share: Undecided
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Hydrocortisone