An interventional study of Dexamethasone and Diclofenac Sodium associated with Codeine in Pain, Edema and Trismus, sponsored by Federal University of the Valleys of Jequitinhonha and Mucuri. Completed at 1 site in Brazil. Open to participants aged 18 Years to 35 Years. Per ClinicalTrials.gov, last updated 2016-08-19.
Sponsored by Federal University of the Valleys of Jequitinhonha and Mucuri · Not applicable, Interventional, and Treatment
The main aim of the study is to investigate the pre-emptive effect of dexamethasone and diclofenac associated to codeine to prevent the pain, edema and limited mouth opening at the extraction of third molar.
The surgery of third molar is usually associated with important post-surgical sequelae. The damage caused to tissue and bone may result in considerable pain, edema and trismus. The symptoms start gradually, peaking in 2 days after the extraction. The use of medications such as dexamethasone and diclofenac associated to codeine may support the prevention of post-surgical pain. This clinical trial aim compare the the pre-emptive effect of dexamethasone and diclofenac associated to codeine to prevent the pain, edema and limited mouth opening at the extraction of third molar.
2,450 studies on the registry are indexed under Pain; 945 are open to participants now.
This study's enrollment of 18 is below the median of 70 across 2,101 interventional studies indexed under Pain.
Browse Pain studies →Federal University of the Valleys of Jequitinhonha and Mucuri is the lead sponsor of 21 studies on the registry; 4 are open to participants now.
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Exclusion Criteria:
Dexamethasone 8 mg, one capsule single preoperative dose.
Drug: Dexamethasone
Diclofenac Sodium 50 mg associated with Codeine 50 mg, one capsule single preoperative dose.
Drug: Diclofenac Sodium associated with Codeine
Dexamethasone 8 mg
Also known as: Dexamethasone Acetate
Diclofenac Sodium 50 mg associated with Codeine 50 mg
Post-surgical swelling of third molar extraction determined using linear measures in the face
During the post-surgical intervals of 24, 48 and 72 hours and seven days, the swelling was determined using linear measures in the face.
Time frame: Up to seven days post-surgical
Post-surgical trismus of third molar extraction determined by maximum mouth opening
During the post-surgical intervals of 24, 48 and 72 hours and seven days, the trismus was determined by maximum mouth opening.
Time frame: Up to seven days post-surgical
Post-surgical pain of third molar extraction using visual analogic scale
The post-surgical pain was self-recorded by the patient using visual analogic scale in intervals of 24, 48 and 72 hours and seven days.
Time frame: Up to seven days post-surgical
Analgesic consumption
Time frame: Up to seven days post-surgical
Duration of surgery
Time frame: Up to seven days post-surgical
The record gives a start of Jan 2016, a primary completion of Jan 2016 and a completion of Jul 2016. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.
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Federal University of the Valleys of Jequitinhonha and Mucuri