A Phase 1/2 interventional study of Transcranial direct current stimulation and Constraint-Induced Movement Therapy in Stroke, Cerebrovascular Disorders and Cerebral Infarction, sponsored by Federal University of Paraíba. Completed at 1 site in Brazil. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2016-04-05.
Sponsored by Federal University of Paraíba · Phase 1/2, Interventional, and Treatment
The purpose is to compare the effects of tDCS and constraint induced movement therapy (CIMT) in the premotor cortex vs. primary motor cortex in severely subacute stroke survivors.
Stroke survivors experience one or more movement-related impairments and activity limitations. In this sense, the premotor cortex (PMC) can be considered as an alternative locus for post-stroke rehabilitation. In relation to physical rehabilitation protocols, associate to neuromodulation, the investigators have chosen a standardized physical therapy protocol for this study, the Constraint Induced Movement Therapy (CIMT), which presents evidence of good therapeutic results. The investigators hypothesized that applying tDCS and CIMT over the PMC promotes motor restoration in stroke patients.
813 studies on the registry are indexed under Cerebral Infarction; 181 are open to participants now.
This study's enrollment of 60 is below the median of 120 across 532 interventional studies indexed under Cerebral Infarction.
Browse Cerebral Infarction studies →Federal University of Paraíba is the lead sponsor of 72 studies on the registry; 6 are open to participants now.
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Exclusion Criteria:
tDCS criteria:
Anodal tDCS on primary motor cortex and CIMT (constraint induced movement therapy)
Device: Transcranial direct current stimulation · Behavioral: Constraint-Induced Movement Therapy
Anodal tDCS on premotor cortex and CIMT (constraint induced movement therapy)
Device: Transcranial direct current stimulation · Behavioral: Constraint-Induced Movement Therapy
Sham tDCS and CIMT (constraint induced movement therapy)
Device: Transcranial direct current stimulation · Behavioral: Constraint-Induced Movement Therapy
Functional Independence measured by Barthel Index
Time frame: Change for functional independence at baseline and week 2
Spasticity (Modified Ashworth Scale)
Time frame: Baseline and Week 2
Muscle strength (Medical Research Council Scale)
Time frame: Baseline and Week 2
This study is completed, as verified in Apr 2016. You cannot join it, but the record below documents what was studied.
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Federal University of Paraíba