An interventional study of caspofungin and corticosteroids in Pneumocystis Pneumonia, sponsored by Beijing Chao Yang Hospital. Status unknown at 1 site in China. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2020-03-13.
Sponsored by Beijing Chao Yang Hospital · Not applicable, Interventional, and Treatment
Pneumocystis Pneumonia is increasing in Immunocompromised Non-HIV Infected Patients. The effects and safety of caspofungin and corticosteroids is not certain in this population. All Immunocompromised Non-HIV patients with respiratory failure were randomized into caspofungin and non-caspofungin group and corticosteroids and non-steroids group. The major outcome is 28 day mortality, the second outcome are time of respiratory rate decreases to less than 25 breath per minute, body temperature lower than 37.3℃.
2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.
This study's planned enrollment of 60 is below the median of 106 across 1,247 interventional studies indexed under Pneumonia.
Browse Pneumonia studies →Beijing Chao Yang Hospital is the lead sponsor of 135 studies on the registry; 49 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
patients treat with caspofungin and corticosteroids on the base of sulfanilamide
Drug: caspofungin · Drug: corticosteroids · Drug: Sulfanilamides
patients treat with caspofungin on the base of sulfanilamide
Drug: caspofungin · Drug: Sulfanilamides
patients treat with corticosteroids on the base of sulfanilamide
Drug: corticosteroids · Drug: Sulfanilamides
patients treat with sulfanilamide only
Drug: Sulfanilamides
70mg ivdrip the first day, then 50mg ivdrip qd
40mg ivdrip q12h for 5 days 40mg ivdrip qd for 5 days 20mg po for 11 days
Also known as: methylprednisolone
1.92g q8h
mortality
Time frame: 28 days
Time for release of fever
Time for body temperature less than 37.3℃ for 48 hours
Time frame: 2 days
Time for release of respiratory distress
Time for respiratory rate \<25 breathes per minute for 48 hours
Time frame: 2 days
This study is status unknown, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.
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Beijing Chao Yang Hospital