An interventional study of CLA and Placebo in Lipid Metabolism Disorders and Obesity, sponsored by Universidade Estadual de Londrina. Completed at 1 site in Brazil. Open to female participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-08-19.
Sponsored by Universidade Estadual de Londrina · Not applicable, Interventional, and Treatment
In this trial, the investigators analyzed the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women.
The aim of this investigation was to analyze the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women. The investigators performed a randomized, double-blinded and placebo-controlled trial with 28 obese women who received 3.2 g/d of CLA or 4 g/d of olive oil (placebo group) while performing an 8-week protocol of aerobic exercise. Dietary intake (food record), body fat (DXA) and biochemical analysis (blood sample) were assessed before and after the intervention period.
997 studies on the registry are indexed under Metabolic Diseases; 234 are open to participants now.
This study's enrollment of 28 is below the median of 48 across 670 interventional studies indexed under Metabolic Diseases.
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Exclusion Criteria:
CLA group received supplementation at a dose of 3.2 g/day (mixture of isomers of CLA isomers predominantly c9, t11 - 50% and c12, t10 - 80%).
Dietary Supplement: CLA
Placebo group received 4 g/day of olive oil.
Behavioral: Placebo
CLA group received supplementation at a dose of 3.2 g/day (mixture of isomers of CLA isomers predominantly c9, t11 - 50% and c12, t10 - 80%). Aerobic exercise associated with CLA
Placebo group received 4 g/day of olive oil. Aerobic exercise
Body fat
Dual-energy X-ray absorptiometry
Time frame: 8 weeks
Total cholesterol
Blood analysis
Time frame: 8 weeks
Triglycerides
Blood analysis
Time frame: 8 weeks
High-density lipoprotein
Blood analysis
Time frame: 8 weeks
Low-density lipoprotein
Estimated by Friedewald formula
Time frame: 8 weeks
Trunk fat
Dual-energy X-ray absorptiometry
Time frame: 8 weeks
Arm fat
Dual-energy X-ray absorptiometry
Time frame: 8 weeks
Leg fat
Dual-energy X-ray absorptiometry
Time frame: 8 weeks
Body mass
Urano, model PS 180
Time frame: 8 weeks
Maximum oxygen uptake
incremental treadmill test
Time frame: 8 weeks
This study is completed, as verified in Aug 2015. You cannot join it, but the record below documents what was studied.
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Universidade Estadual de Londrina